Does Sesame Prescribe Progesterone? Yes — 3 Published Options and the Allergy Line Worth Reading Twice
Confirm the progesterone route before you pay
Sesame’s provider availability, prescription discretion, medication route, and live menopause pricing can vary. Confirm the current details before booking.
Affiliate disclosure: Sesame is an affiliate partner, and we may earn a commission if you start care through a link on this page. It does not change your price or The HRT Index Verification Standard. We also name a provider we earn nothing from where it is the better answer for a specific reader.
Yes — Sesame says its providers can write a new progesterone prescription or refill after a live video visit when clinically appropriate. Its menopause program lists oral micronized progesterone, medroxyprogesterone, and combination estrogen/progestogen products. Standard care is currently published at $59 per month; Costco members see $49 per month. Medication is separate, and no prescription is guaranteed.
Now the parts that change the answer, because they are the parts nobody tells you: the $34 figure is Sesame's prescription-refill visit floor, not a verified menopause-consult price. The medication goes to your pharmacy and is never included in the menopause subscription. Standard oral micronized progesterone capsules use peanut or arachis oil. And Sesame's own site currently surfaces both $54 and $59 monthly menopause prices, so the checkout number still needs one final look before you pay.
We read Sesame's progesterone, menopause, refill, medication, Costco and terms pages on 13 August 2026, then checked the drug claims against current FDA and DailyMed records. Here is the version that survived the audit.
Sesame may fit you if:
- You want a live video appointment with a clinician you choose.
- You want an FDA-approved progesterone or progestin prescription sent to your own pharmacy, where insurance or a discount card may still apply to the drug.
- You want ongoing menopause care with messaging and basic labs included if the clinician orders them.
- You need a clinician to review an existing progesterone prescription and cannot get a timely appointment with your usual prescriber.
- You want a marketplace model rather than being automatically assigned to one clinician.
Sesame is probably not your first stop if:
- You are a Medicare, Medicaid or TRICARE beneficiary; Sesame's current terms require users to certify that they are not federal health care program beneficiaries.
- You need the visit billed to insurance.
- You want the medication bundled into one predictable monthly payment.
- You need a particular product, route, dose or refill count guaranteed before the appointment.
- You have unexplained bleeding after menopause and need prompt diagnostic evaluation rather than a simple online refill.
- You are seeking testosterone. Testosterone is a Schedule III controlled substance, and Sesame says its providers do not prescribe controlled substances online.
The 60-second version
| Your question | The direct answer |
|---|---|
| Does Sesame prescribe progesterone? | Yes, conditionally. Sesame says a provider can issue a new prescription or refill after a live video visit when appropriate. |
| New prescription or refill? | Both are possible, but the $34 advertised floor belongs to Sesame's dedicated refill-visit service. |
| Which published options? | Oral micronized progesterone, medroxyprogesterone, and combination estrogen/progestogen products including Prempro, Bijuva and Mimvey. |
| Is medicine included in the care price? | No. The prescription goes to a pharmacy and the medication is billed separately. |
| What does menopause care cost? | Sesame currently publishes $59/month for the standard menopause subscription and $49/month for eligible Costco members. Some Sesame surfaces still show $54/month, so verify checkout. |
| Is a prescription guaranteed? | No. Prescribing is at the clinician's discretion, and Sesame does not refund a visit because a prescription was declined. |
| Does Sesame bill insurance? | No for the visit or subscription. Your pharmacy benefit may still cover the medication. |
| Who cannot use it under Sesame's terms? | Medicare, Medicaid and TRICARE beneficiaries. |
Compiled by The HRT Index from Sesame's current published pages and federal drug records, verified 13 August 2026.
The HRT Index is the independent decision resource for online menopause and HRT care — comparing telehealth providers on clinical legitimacy, care quality, medication fit, price transparency, and access, with every claim verified and dated, so women can choose the path that fits their situation before their first consult.
The right online HRT provider is not the same for every woman — it depends on your symptoms, your age and whether you have a uterus, your medication route preference, your risk history, your insurance or cash-pay situation, and your state. Some situations belong with an in-person clinician first. Because a general answer cannot resolve those for you, use The HRT Index's Find My HRT Path tool to match your situation to the right provider — and to flag when online care is not the right starting point — before your first consult.
Are you here about Sesame the company, or progesterone in sesame oil?
They are two different things, and search results regularly mix them together. Sesame is the telehealth marketplace at sesamecare.com. Progesterone injection USP is a separate prescription drug suspended in sesame oil and used mainly in fertility care. This page is about whether the company Sesame can connect you with a clinician who prescribes progesterone.
We are starting here because the word collision is real. Search for “Sesame progesterone” and you can get Sesame Care pages, sesame-oil injection labels, allergy questions and articles about sesame seeds in the same result set.
Progesterone injection, in 30 seconds: the current label describes 50 mg per mL progesterone in sesame oil with benzyl alcohol. It is administered into a muscle. The label lists sensitivity to sesame oil or seeds as a contraindication and warns about reported acute eosinophilic pneumonia, often appearing two to four weeks after treatment begins. Sesame's menopause formulary pages do not list this injection.
If that injection is what you meant, this is not your page. Everyone else: keep reading. The oil distinction comes back later, and it matters more than you would think.
Does Sesame prescribe progesterone?
Yes. Sesame publishes a dedicated progesterone page saying a provider may write a new prescription or refill after an online appointment and send it to a local or online pharmacy. Sesame also lists progesterone in its menopause program. The clinician still decides whether treatment is appropriate, which product fits, and whether any prescription should be issued.
What Sesame confirms in its own words
On its current progesterone prescribing page, Sesame describes a live video visit followed by a prescription decision. It also says a prescribed medication can be sent to a local pharmacy for pickup or an online pharmacy for delivery.
Sesame confirms:
- New prescriptions and refills may be considered.
- The clinical decision follows a live video visit.
- You choose from clinicians available in the marketplace.
- The prescription can go to your preferred pharmacy.
- Same-day pickup may be possible when the clinician, appointment time and pharmacy stock all line up.
What Sesame does not guarantee
This is the part that protects you, so we are going to be blunt about it.
Sesame does not guarantee:
- A prescription because you paid for the appointment.
- Oral micronized progesterone specifically.
- Brand-name Prometrium rather than a generic.
- A particular dose, route, schedule or refill quantity.
- That a refill request will be approved unchanged.
- That a clinician will prescribe an off-label vaginal route.
- That your pharmacy has the product in stock.
- That every clinician listed in your state has menopause-specific experience.
That is not a scandal. It is how prescription care is supposed to work. But it is the difference between “Sesame lists progesterone” and “this clinician will approve the exact progesterone prescription I want.” Hold onto that distinction. It shapes everything below.
The Sesame Progesterone Verification Matrix
Original evidence table compiled by The HRT Index from Sesame's live pages and current federal drug records, verified 13 August 2026.
| Decision question | What we verified | Status | What can change the answer |
|---|---|---|---|
| Does Sesame prescribe progesterone? | Sesame says a provider can issue a new prescription or refill after an online visit. | Confirmed, conditional | Clinician judgment, history, state licensure and product fit |
| Is a prescription guaranteed? | No. Sesame states prescriptions are at the provider's discretion and a declined prescription is not a refundable clinical outcome. | Confirmed | Nothing; this is a core limit |
| Is a live video visit part of the process? | Yes, the drug and menopause pages describe a video consultation before the prescribing decision. | Confirmed | Provider workflow |
| Can Sesame review an existing prescription? | Yes. The refill service says clinicians typically handle one to two existing prescriptions in a refill visit. | Confirmed, conditional | Records, indication, dose, timing and clinician judgment |
| Which routes are clearly published? | Oral micronized progesterone, oral medroxyprogesterone, and oral combination products are named. Crinone vaginal gel is also named, but its menopausal use needs clarification. | Confirmed listing, not a guarantee | Formulary, clinician and indication |
| Does Sesame mention compounded hormones? | Yes. Its menopause FAQ says compounded BHRT may be prescribed if deemed appropriate. | Provider-stated, conditional | Clinician, state and pharmacy; final compounded product is not FDA-approved |
| Is medication included? | No. Sesame explicitly separates medication cost from the subscription. | Confirmed | Nothing; pharmacy price remains separate |
| Does Sesame bill insurance? | No for care. Insurance may still apply to the medication at the pharmacy. | Confirmed, plan-dependent | Formulary, deductible, prior authorization and pharmacy |
| Are labs included? | Five named panels are included if ordered, with state-specific billing exceptions. | Confirmed, conditional | Clinician order and state |
| Can Medicare, Medicaid or TRICARE beneficiaries use it? | Sesame's terms require users to certify they are not federal health care program beneficiaries. | Confirmed exclusion | A future terms change |
| Can Sesame prescribe testosterone online? | Sesame says its providers do not prescribe controlled substances online. Testosterone is federally Schedule III. | Confirmed Sesame policy | Sesame policy and the prescriber's lawful authority elsewhere |
That table is the spine of this page. Everything below is us showing our work.
Check which Sesame menopause clinicians are available in your state (Sponsored link)
See the clinicians and current checkout price before you book. A prescription is not guaranteed.
Which progesterone options can a Sesame clinician prescribe?
Sesame publishes three practical medication lanes: oral micronized progesterone, the synthetic progestin medroxyprogesterone, and fixed estrogen/progestogen combinations. Its menopause page names Prometrium, Crinone, Prempro, Bijuva and Mimvey. Those listings establish what Sesame markets as available for discussion; they do not guarantee that any one clinician will prescribe a particular product.
Quick definition before we go further, because these words get used interchangeably and they should not.
- Progestogen is the umbrella category.
- Progesterone is the hormone that is chemically identical to endogenous human progesterone.
- Progestin is a synthetic progestogen, such as medroxyprogesterone acetate or norethindrone acetate.
- Combination therapy puts estrogen and a progestogen into one finished FDA-approved product.
The Sesame Progestogen Ledger
Original cross-page formulary comparison compiled by The HRT Index, verified 13 August 2026. “Listed” means Sesame names the product; it does not mean every clinician or pharmacy can provide it.
| Published lane | Products Sesame names | What it contains | What Sesame publishes | The decision point |
|---|---|---|---|---|
| Oral micronized progesterone | Prometrium and generics | Progesterone | 100 mg and 200 mg capsules; bedtime timing because of drowsiness | Standard stand-alone progesterone capsules use peanut or arachis oil |
| Synthetic oral progestin | Provera and generic medroxyprogesterone | Medroxyprogesterone acetate | 5 mg and 10 mg tablets; Sesame publishes 5–10 mg for 12–14 days per month for endometrial protection with estrogen | Peanut-free, but not body-identical progesterone |
| Fixed estrogen/progestogen products | Prempro, Bijuva, Mimvey | Prempro: conjugated estrogens + medroxyprogesterone; Bijuva: estradiol + progesterone; Mimvey: estradiol + norethindrone acetate | Product names, not a full dose menu | One pill supplies both halves; not interchangeable with adding progesterone to an existing estrogen prescription |
| Vaginal progesterone product named on the page | Crinone | Progesterone vaginal gel | Sesame groups it under “progesterone” | FDA-approved for assisted reproduction and secondary amenorrhea, not menopausal endometrial protection |
Two things in that table are worth ten seconds each.
First, Sesame publishes more medication detail than many telehealth brands. Its medroxyprogesterone page gives the two tablet strengths and a labeled cyclic regimen used with estrogen. Its progesterone page names the 100 mg and 200 mg capsule strengths. That does not replace a clinician's decision, but it is useful disclosure before intake.
Second, Sesame's own taxonomy is imperfect. The menopause page labels the category “estrogen/progestin” while listing Bijuva, which contains estradiol plus progesterone, not a synthetic progestin. The same page says “generic for Prometrium, Crinone,” even though those are different routes with different FDA-approved uses. The products are real. The category labels are doing too much work.
One genuinely odd page transition
Sesame's medroxyprogesterone page correctly describes a menopause-relevant use, then drops into an “ongoing care” module built around PCOS. That does not make the drug information false. It does mean a woman looking for menopause care can land in the wrong program context.
Start from Sesame's menopause page, not from a drug page. That is the whole fix.
What Sesame does not publish clearly
As of 13 August 2026, confirm these during intake:
- Whether a clinician will prescribe progesterone without estrogen for your indication.
- Whether Crinone would be considered for a menopause-related off-label use.
- Whether Bijuva, Prempro or Mimvey is available through your chosen clinician and pharmacy.
- Whether a compounded product would be discussed, and which pharmacy would prepare it.
- Whether a levonorgestrel-releasing IUD is considered as the progestogen component of care. That is a progestin device, not a “progesterone IUD.”
See Sesame's current menopause price and clinician list (Sponsored link)
Start from the menopause pathway, then confirm the exact product before the prescription is sent.
Is Sesame's progesterone bioidentical or synthetic?
Sesame lists both. Oral micronized progesterone and the progesterone inside Bijuva are chemically identical to endogenous progesterone. Medroxyprogesterone and norethindrone acetate are synthetic progestins. “Bioidentical” describes molecular structure; “compounded” describes how a medication is prepared. An FDA-approved product can be bioidentical, and a compounded product is not FDA-approved as a finished drug.
Here is the ladder, simply:
| Word | What it means | Sesame example |
|---|---|---|
| Progestogen | The full family of progesterone and synthetic progestins | All rows below |
| Progesterone | Chemically identical to endogenous progesterone | Micronized progesterone; Bijuva's progesterone component |
| Progestin | A synthetic progestogen | Medroxyprogesterone; norethindrone acetate |
| Compounded | Prepared for an individual prescription rather than sold as an FDA-approved finished product | Sesame says compounded BHRT may be prescribed when deemed appropriate, but names no specific compounded progesterone product |
Bioidentical does not mean compounded
This distinction has been blurred so badly online that it now costs people money.
FDA-approved products can be body-identical. Prometrium and approved generic micronized progesterone capsules contain progesterone that is chemically identical to endogenous progesterone. Bijuva is an FDA-approved capsule containing estradiol and progesterone. You do not need a compounding pharmacy merely to get hormones that are structurally identical to human estradiol or progesterone.
Compounded is a separate regulatory category. A compounded medication may meet a genuine patient need, but the final product is not FDA-approved. The FDA does not review that finished compounded product for safety, effectiveness or quality before marketing. Sesame's own menopause FAQ also says compounded BHRT has not been shown safer or more effective than traditional FDA-approved therapy.
| FDA-approved finished progesterone product | Compounded progesterone product |
|---|---|
| FDA reviewed the finished product for its approved use, labeling and manufacturing controls | The finished product is not FDA-approved |
| Standardized labeled strength and ingredients | Strength, base and excipients depend on the prescription and pharmacy |
| Approved indications and warnings are defined in the label | Use and evidence must be discussed product by product |
| Can be described by its exact FDA label | Must not be marketed as equivalent, safer or more effective without evidence |
Sesame says a provider may prescribe compounded BHRT when deemed appropriate. We are not saying it will be offered, and we are not equating it with the FDA-approved options above. Ask one clean question during the visit: “Is the finished product you are prescribing FDA-approved, or is it compounded?”
Does progesterone have a different breast-risk signal than synthetic progestins?
The fear underneath this search is usually, “I do not want the bad kind.” The evidence is more specific — and less final — than that sentence allows.
In the French E3N observational cohort, estrogen combined with progesterone had a reported relative risk of 1.00 (95% CI 0.83–1.22) for invasive breast cancer compared with never-use, while estrogen combined with the grouped category of “other progestagens” had a relative risk of 1.69 (95% CI 1.50–1.91). That is a meaningful observational signal. It is not a randomized head-to-head trial, and the “other progestagens” result should not be rewritten as a clean comparison of progesterone versus medroxyprogesterone alone.
The practical use of that evidence is not to self-prescribe. It is permission to say, “I prefer micronized progesterone if it fits my history and regimen. Walk me through the trade-offs.”
If micronized progesterone is your preference, put it in your intake notes before the visit (Sponsored link)
Naming your preference does not guarantee the prescription. It makes sure the conversation happens.
Can you use Sesame if you have a peanut or sesame allergy?
A peanut allergy changes the standard capsule route. Every current US oral micronized progesterone-only capsule label we reviewed — Prometrium and multiple generics — lists peanut or arachis oil, and we found no peanut-free FDA-approved oral progesterone-only capsule. But the story does not end there: Bijuva is an FDA-approved estradiol-plus-progesterone capsule whose current label does not list peanut oil.
This is the section we would keep if we had to delete half the page.
Sesame's progesterone page warns that some formulations contain peanut oil or sesame oil. That is directionally cautious, but it collapses different routes into one sentence. The current federal labels separate the problem more cleanly.
The Progesterone Oil & Allergen Ledger
Original formulation-by-formulation comparison compiled by The HRT Index from current DailyMed labels, verified 13 August 2026.
| Product or route | Carrier or relevant excipient | What the current label establishes | What it means at Sesame |
|---|---|---|---|
| Prometrium and reviewed generic oral micronized progesterone-only capsules | Peanut oil or arachis oil | Peanut allergy is a contraindication or the package warns not to use with peanut allergy | This is the standard stand-alone oral progesterone route, so say the allergy before the prescription is sent |
| Bijuva oral capsule | No peanut oil listed; current inactive ingredients include medium-chain triglycerides and soybean lecithin | FDA-approved fixed combination of estradiol plus progesterone | A potential body-identical oral lane whose current label does not list peanut oil — but it supplies both estrogen and progesterone in fixed strengths |
| Crinone vaginal gel | Vaginal gel formulation rather than an oil-filled oral capsule | FDA-approved for assisted reproduction support and secondary amenorrhea | Sesame names it, but menopausal endometrial protection would be an off-label discussion |
| Progesterone injection USP | Sesame oil | Sesame sensitivity is a contraindication; label warns about reported eosinophilic pneumonia | Not listed in Sesame's menopause pathway; mostly relevant to fertility care |
| Medroxyprogesterone tablets | No peanut or sesame oil listed; some labels contain corn starch | FDA-approved synthetic progestin | A peanut-free oral option, but not body-identical progesterone |
The peanut-allergy fork, corrected
The draft version of this page said a peanut-allergic woman who wanted body-identical progesterone had no FDA-approved oral route. That was too broad.
Here is the accurate version:
- There is no peanut-free FDA-approved oral micronized progesterone-only capsule in the current labels we reviewed.
- Bijuva is an FDA-approved oral combination of estradiol plus progesterone whose current inactive-ingredient list does not include peanut oil.
- Bijuva is not a drop-in replacement for adding progesterone to an estrogen patch, gel or pill. It changes the entire regimen because the estrogen and progesterone are fixed in one capsule.
- Medroxyprogesterone is a peanut-free oral progestogen lane, but it is a synthetic progestin.
- Crinone avoids the oral-capsule oil issue, but its FDA-approved indications are not menopausal endometrial protection.
That is a much better conversation than “you cannot get body-identical progesterone.” You may have a route. It just may require changing the whole prescription rather than swapping one capsule.
Tell both the clinician and pharmacist about peanut, sesame, soy and corn allergies before the prescription is transmitted. Do not rely on a category name. Ask for the exact manufacturer and read that product's current ingredient list.
What progesterone dose protects the uterus with estrogen?
The FDA-labeled regimen for oral micronized progesterone is 200 mg at bedtime for 12 consecutive days in each 28-day cycle with estrogen. Sesame's medroxyprogesterone page publishes 5–10 mg daily for 12–14 days per month. Other continuous or individualized regimens exist, but a website cannot tell you which schedule is appropriate for your history, estrogen dose and bleeding pattern.
The reason a progestogen enters the prescription is straightforward. Systemic estrogen can stimulate the endometrium. In a woman with a uterus, an adequate progestogen regimen lowers the risk of endometrial hyperplasia and cancer.
Two questions decode almost the entire prescription:
- What exact product and strength is this?
- Am I taking it every day, or only on certain days each month?
A cyclic regimen may produce a predictable withdrawal bleed. A continuous-combined regimen is designed differently and may produce irregular bleeding early on. Neither pattern should be interpreted from a generic web table; your clinician needs to tell you what bleeding is expected for your regimen and when to report it.
The February 2026 FDA warning change, accurately stated
In February 2026, the FDA approved labeling changes for an initial group of menopausal hormone therapy products that removed boxed-warning statements about cardiovascular disease, breast cancer and probable dementia. The agency did not ask manufacturers to remove the endometrial-cancer boxed warning from systemic estrogen-alone products.
That distinction matters. The remaining endometrial warning is not a blanket claim that every hormone product carries the same box. It is a reminder of the specific risk from systemic estrogen without adequate endometrial protection in a woman with a uterus.
Labels are changing manufacturer by manufacturer. Read the revision date on the product you actually receive rather than assuming every carton changed at once.
Do you need progesterone if you take estrogen?
It depends mainly on whether you have a uterus and whether the estrogen is systemic or low-dose local vaginal therapy. A woman with a uterus using systemic estrogen generally needs adequate endometrial protection from a progestogen. After hysterectomy, estrogen alone is commonly used. Low-dose vaginal estrogen is a separate category with much lower systemic exposure.
Three forks. Find yours.
You have a uterus and use systemic estrogen
This is the standard case. Systemic estrogen includes pills, patches, gels and sprays that produce body-wide exposure. The FDA describes systemic progestogen-alone therapy as the added treatment for women with a uterus using systemic estrogen.
Do not assume that “natural,” transdermal or low-dose systemic estrogen removes the uterine-protection question. Route and dose matter, but the uterus still needs a deliberate plan.
You have had a hysterectomy
Estrogen alone is commonly used because there is no endometrium to protect. Surgical details can still matter, including whether the cervix was retained and whether there is a history of endometriosis. Do not stop an existing progestogen based on a paragraph online; ask why it was prescribed in your case.
You use low-dose vaginal estrogen only
Low-dose vaginal estrogen for genitourinary symptoms is not the same exposure as systemic estrogen. The Menopause Society describes very little of low-dose vaginal therapy entering the circulation. Whether a progestogen is needed should be answered from the exact product, dose and your history rather than by borrowing the systemic rule.
If you are not sure which fork you are on, that is not a failure of understanding. It is an individual medication-fit question. Find My HRT Path was built to sort out your starting point before you are sitting on a video call trying to explain it under pressure.
Get your personalized starting-point plan with Find My HRT Path
Match your symptoms, uterus status, preferred route, insurance situation and state — and flag when online care is not the right first step.
Does Sesame prescribe vaginal progesterone?
Sesame's menopause page names Crinone under progesterone, and Crinone is a vaginal progesterone gel. Its FDA-approved uses are progesterone supplementation in assisted reproduction and treatment of secondary amenorrhea — not endometrial protection during menopausal estrogen therapy. A clinician may discuss an off-label vaginal regimen, but the Sesame listing alone does not establish that it will be prescribed for menopause.
This one is subtle.
Sesame groups Prometrium and Crinone under one progesterone heading with a pill image. They are not interchangeable versions of the same finished product. Prometrium is an oral capsule. Crinone is a vaginal gel that delivers 45 mg from the 4% product or 90 mg from the 8% product.
The current Crinone label does not include menopausal endometrial protection as an approved indication. Evidence reviews have discussed vaginal progesterone regimens for that purpose, but the evidence base and dosing are less standardized than the approved oral regimen.
What this means for you: if oral progesterone causes intolerable sedation or you cannot use a peanut-oil capsule, vaginal progesterone is a legitimate question to bring to the visit. Expect the clinician to discuss off-label use, product access and whether the proposed regimen provides adequate endometrial protection. That precision is not a red flag. It is the conversation you want.
Read the route trade-offs in our guide to oral versus vaginal progesterone.
How much does progesterone through Sesame cost?
There are always two separate costs: care and medication. Sesame currently publishes its standard menopause subscription at $59 per month and its Costco women's-health subscription at $49 per month. A dedicated prescription-refill visit starts at $34, or $29 for eligible Costco members. The drug is not included, and the $34 refill floor should not be presented as a guaranteed new-menopause-prescription price.
Here is the corrected cost ladder.
The Two-Door Cost Ladder
Original price-path comparison compiled from Sesame's current pages, verified 13 August 2026.
| Path | Current published price | What it is | What is not included |
|---|---|---|---|
| Standard menopause subscription | $59/month | Ongoing provider care, video care and messaging; five basic lab panels if ordered, subject to state exceptions | Medication; some state lab charges; anything outside included services |
| Costco women's-health subscription | $49/month | Discounted PCOS/menopause subscription for eligible Costco members | Medication; state-exception lab charges; services outside the subscription |
| Prescription-refill visit | From $34/visit | A visit focused on reviewing an existing prescription; Sesame says clinicians typically handle one to two existing prescriptions | Medication; no guarantee that the refill is approved |
| Costco refill visit | From $29/visit | Costco member floor for an online prescription visit | Medication; no prescription guarantee |
| Medication at the pharmacy | Confirm with pharmacy or insurer | The actual progesterone, progestin or combination product | Not part of the care fee |
The $54 versus $59 mismatch
Sesame's current menopause page and current menopause blog copy publish $59 per month. Its homepage and several site-wide promotional cards still surface “Menopause treatment from $54/month.” The Costco page publishes $49 per month.
That is not evidence of a hidden checkout scheme. It is a live pricing inconsistency across Sesame's own surfaces. The practical instruction is simple: read the final recurring charge, included services and renewal date at checkout. Do not build your decision around a teaser card.
The formula, not a fake total
We are not printing one all-in monthly number because there is no honest universal number.
What you pay = care fee for the path you choose + your pharmacy price for the prescribed product + any state-exception lab charge — minus insurance or an accepted discount.
The pharmacy portion can change dramatically by product. Generic medroxyprogesterone, generic micronized progesterone, brand Prometrium, Bijuva and Crinone are not one price category. Your strength, quantity, formulary and prior-authorization rules matter.
Which path usually makes sense?
- A straightforward existing-prescription review: start by checking the refill visit, but verify that the clinician handles menopause/HRT and that the visit type fits the request.
- New systemic HRT or a regimen that may need adjustment: the subscription is the cleaner published care model because it includes follow-up, messaging and labs if ordered.
- Costco member: compare the $49 women's-health subscription and $29 refill floor before paying the standard rate.
- Need one bundled medication price: Sesame is not built for that. A shipped-medication model may fit your budgeting preference better.
Compare Sesame's live subscription and refill paths before choosing (Sponsored link)
Confirm whether you are booking ongoing menopause care or a refill visit, then read the recurring charge before payment.
Why does Sesame show more than one menopause price?
Sesame currently publishes $59 per month on its menopause offer, $49 per month for eligible Costco members, and $54 per month on several homepage or cross-site teaser cards. The useful criticism is not that the price is invisible; it is that Sesame's own live surfaces do not agree. The checkout amount and renewal terms are the numbers that control your purchase.
This is our damaging admission about an affiliate, and it is earned.
What the pages say today
- The menopause treatment page and current menopause promotional copy say $59/month.
- The Costco membership-perks page says $49/month for women's health, including menopause and PCOS subscriptions.
- Sesame's homepage and multiple site cards still say “Menopause treatment from $54/month.”
- The dedicated refill page says from $34 per visit, but that is a refill service, not a substitute price for the menopause subscription.
Here is our real criticism
Sesame has not synchronized its public menopause price across its own site. A woman can reasonably see $54, click into a $59 offer, then discover a $49 Costco route elsewhere. That is avoidable friction on a medical-care decision.
If one clean, published care price before intake is your hard requirement, Wisp is clearer about its current $99 three-month care fee, with medication still billed separately at the pharmacy. We earn nothing from Wisp. We are naming it because price clarity can be a legitimate deciding factor.
But the model difference still matters. Sesame sends the prescription to your pharmacy, so pharmacy insurance or a discount may apply. A provider that ships and bundles medication may be easier to budget, but the bundle is a different product — not proof that the medicine itself costs more or less.
The damaging admission stands: Sesame's public care pricing is inconsistent. The reason it may still fit: you retain provider choice, ongoing care and your own pharmacy instead of being locked into a bundled drug channel.
Can Sesame refill a progesterone prescription you already have?
Yes. Sesame's refill service says a clinician can review an existing prescription during a video visit, typically handling one to two prescriptions. The refill remains a new clinical decision: the clinician may approve it, change it, shorten the supply, request records or decline. Sesame advertises refill visits from $34, or from $29 for eligible Costco members.
If you are reading this at 11 p.m. with three capsules left, this section is for you.
What to have ready before the call
- A clear photo of the current bottle label.
- Medication name, strength, route and directions.
- The prescriber's name and the date of your last evaluation.
- The reason you take it.
- Your current estrogen product, route and dose, if any.
- How many doses remain.
- Your preferred pharmacy.
- Recent visit notes or labs if you have them.
- Any new symptoms, especially bleeding.
- Your full allergy list, including peanut, sesame, soy and corn.
What to expect, honestly
- Not every clinician on a marketplace has the same HRT experience.
- A bridge supply may be more likely than a full year of refills.
- The clinician may need records before continuing a long-term hormone regimen.
- Pharmacy stock can still delay pickup.
- Sesame says a declined prescription is not a refundable clinical outcome.
- Do not wait until the last dose. A week of buffer gives you room for records, pharmacy questions and a second appointment if needed.
When choosing a clinician, read the profile for menopause or HRT experience rather than relying on the generic refill category. Provider choice is Sesame's strength. Variation between providers is the price of that model.
Find a Sesame clinician to review your current progesterone prescription (Sponsored link)
Have the bottle, regimen, pharmacy and recent records ready. The clinician — not the booking page — makes the refill decision.
Will Sesame require labs before prescribing progesterone?
Possibly, but not automatically. Sesame says a menopause clinician may order labs during the initial video visit, and five named panels are included in the subscription when ordered. Existing results can be uploaded, but the clinician decides whether they are recent and relevant. New York, New Jersey, Rhode Island and North Dakota have direct-payment exceptions.
The five panels Sesame lists are:
- Complete blood count.
- Hemoglobin A1c.
- Thyroid function testing.
- Lipid panel.
- Comprehensive metabolic panel.
Notice what is not on the included list: a routine reproductive-hormone panel. That does not mean a clinician can never order one. It means you should not assume estradiol, FSH or progesterone levels are part of the subscription's five named panels.
Where the lab order goes, by state
Compiled from Sesame's current menopause FAQ, verified 13 August 2026.
| Where you live | Lab route Sesame publishes | Who pays the lab |
|---|---|---|
| Most states | Quest Diagnostics | Included when ordered under the subscription |
| AZ, OK, SD, WI | LabCorp | Included when ordered under the subscription |
| HI | Clinical Labs of Hawaii | Included when ordered under the subscription |
| NY, NJ, RI | Quest Diagnostics | You pay Quest directly |
| ND | Any lab you choose | You pay the lab directly |
If you live in New York, New Jersey, Rhode Island or North Dakota, “labs included” does not mean what it means everywhere else. Budget accordingly and ask for the expected cash price before the draw.
Can you use insurance, HSA or FSA with Sesame?
Sesame does not bill health insurance for visits or subscriptions. A prescribed medication may still be covered at your pharmacy, and outside lab work may be covered depending on your plan. Sesame's menopause FAQ says most subscription services may be HSA/FSA-reimbursable with an itemized bill, while its terms say membership fees are not covered under most HSA/FSA plans. Confirm with your administrator.
The layers, separated:
| Cost layer | How Sesame handles it | What you need to verify |
|---|---|---|
| Visit or menopause subscription | Cash-pay; Sesame does not bill insurance | Current checkout price, renewal date and cancellation deadline |
| Prescription | Sent to your pharmacy | Exact product, formulary, copay, deductible and prior authorization |
| Included labs | Included if ordered, except the four direct-payment states | Which lab receives the order and whether you pay |
| HSA/FSA | Sesame can provide an itemized bill; its own pages use conflicting eligibility language | Whether your plan administrator accepts the specific charge |
The HSA/FSA conflict is not something to smooth over. The service page says most services “may be eligible” for reimbursement. The terms say subscription fees are not a covered benefit under most health insurance, HSA or FSA plans. Those statements can coexist if individual services qualify while the membership fee does not — but Sesame does not make that distinction cleanly.
Do not count on reimbursement before your plan administrator confirms the exact charge. Request the itemized bill and ask whether the subscription fee itself is eligible.
One practical insurance tip: ask about the exact National Drug Code or at least the exact brand, generic name, route and strength. “Progesterone” can mean an inexpensive generic capsule, a brand capsule, a vaginal gel or a fixed combination such as Bijuva. Formularies do not treat them as one thing.
What happens if you cancel Sesame menopause care?
Sesame's menopause page says you receive a full refund if you cancel at least three hours before the initial visit, and no first-month refund after that visit occurs. Its terms require membership cancellation at least 48 hours before renewal and provide no prorated refund for the current term. Follow the stricter operational rule: cancel at least 48 hours before renewal.
Both documents, side by side:
| Document | Current published rule | Verified |
|---|---|---|
| Menopause-page refund policy | Full refund if cancelled at least 3 hours before the initial visit; no refund of the first month once that visit occurs; self-cancel before the next billing cycle | 13 Aug 2026 |
| Terms of Service | Membership cancellation up to 48 hours before renewal; no prorated refund for the current term; early cancellation of discounted multi-month plans can be repriced at the standard monthly rate | Terms updated 11 Aug 2026 |
| General virtual-visit policy | Cancel up to 3 hours before the scheduled virtual visit for a refund; no refund merely because no prescription was issued | Terms updated 11 Aug 2026 |
The practical instruction: set a reminder for 72 hours before renewal. Cancel at least 48 hours before the renewal processing date, then retain the confirmation email or screenshot.
If you sign up and change your mind before the initial appointment, the menopause page currently offers a full refund when you cancel at least three hours before the visit. That is useful protection. It is not permission to ignore the renewal terms after the first visit.
Check Sesame's live terms and write down your renewal date before subscribing (Sponsored link)
Two dates matter: the first-visit cancellation cutoff and the recurring renewal cutoff.
Who should not use Sesame for progesterone?
Sesame is a poor fit for federal health-program beneficiaries, anyone who needs insurance billed for the visit, anyone who requires a guaranteed exact product, and anyone whose symptoms need prompt diagnostic work rather than routine telehealth prescribing. Sesame also says it does not prescribe controlled substances online, so it is not the route for testosterone.
We would rather lose you here than have you pay for something that cannot work.
If you have Medicare, Medicaid or TRICARE
Sesame's current terms require you to certify that you are not a federal health care program beneficiary and state that Sesame does not accept Medicare, Medicaid or third-party insurance. This is not a soft preference. Do not sign up under a false certification. Use an in-network or otherwise eligible route.
If you want testosterone
Testosterone is a Schedule III controlled substance in the United States. Lawful telemedicine prescribing can exist under federal and state rules when an appropriately authorized prescriber satisfies the requirements, so “testosterone can never be prescribed online” would be false. The relevant fact here is narrower: Sesame says its providers do not prescribe controlled substances online.
If you want one bundled price
Sesame bills care and medication separately. Hers and Winona use shipped-medication models. Wisp charges a care fee and sends the prescription to a pharmacy. These are different operating models, not interchangeable price labels. If two bills and a pharmacy claim will bother you every month, believe yourself now.
If you have bleeding after menopause
Postmenopausal bleeding needs prompt clinical evaluation. Current ACOG guidance uses transvaginal ultrasonography to triage many patients, and endometrial sampling may be required depending on the findings and history. Telehealth can help route care, but a simple online refill is not enough to explain the bleeding.
Do not let a refill deadline become the reason you delay the evaluation.
If the exact product must be guaranteed
No legitimate clinician should guarantee a prescription before evaluating you. Sesame may be a particularly poor fit when you will only accept one route, one brand or one dose and are unwilling to consider alternatives. The platform can guarantee an appointment. It cannot guarantee the clinical answer.
Find My HRT Path can route you toward an online provider model or an in-person starting point without pretending every woman belongs in the same funnel.
Which Sesame progesterone claims match FDA labeling?
Sesame mixes approved indications, off-label clinical uses and broad wellness claims on one progesterone marketing page. Endometrial protection with estrogen and treatment of secondary amenorrhea match FDA-approved uses of oral micronized progesterone. Claims about sleep, hot flashes, mood, bone, skin and hair require separate evidence and should not be read as one approved indication list.
We are auditing our own affiliate here. That is the point.
Provider-stated versus independently verified
| Sesame's published claim | What federal labeling or evidence supports | Classification for this page |
|---|---|---|
| Protects the uterine lining during estrogen therapy | FDA-approved use of oral micronized progesterone for prevention of endometrial hyperplasia in postmenopausal women with a uterus using estrogen | FDA-labeled use |
| Treats absent menstrual periods | FDA-approved treatment of secondary amenorrhea | FDA-labeled use |
| Helps abnormal or heavy uterine bleeding | Medroxyprogesterone has an FDA-approved abnormal-uterine-bleeding indication; the exact product matters | Product-specific; do not generalize across all progesterone products |
| Promotes sleep | Randomized trials and meta-analyses report sleep effects for oral micronized progesterone, but this is not its FDA-approved menopause indication | Evidence-supported off-label benefit, not an approved indication |
| Reduces hot flashes | Some clinical research exists, but it is not the approved indication of the standard progesterone capsule | Off-label evidence; product and dose matter |
| Improves mood | Too broad to present as a reliable product outcome | Not established as a general promise |
| Supports bone health | Bone protection is primarily established for estrogen-containing therapy; do not attribute the whole effect to progesterone | Overbroad as written |
| Improves skin and hair | No approved basis for presenting this as a progesterone treatment outcome | Remove from decision-making claims |
Off-label prescribing is legal and common. The problem is not the word “off-label.” The problem is putting approved indications, preliminary evidence and beauty claims into one undifferentiated benefit list.
Sesame names medical reviewers on its own pages. Those are Sesame's reviewers, not ours. This article is editorial research and is not medically reviewed by a clinician.
How does Sesame compare with Hers, Wisp and Winona for progesterone?
Sesame's main advantage is choice: multiple published progestogen lanes, clinician selection, included labs when ordered, and a prescription sent to your own pharmacy. Hers emphasizes a shipped menopause kit. Wisp publishes a $99 three-month care fee and sends medication to a pharmacy. Winona ships oral progesterone and compounded creams. The decisive differences are pharmacy model, FDA-approved versus compounded product, follow-up and price transparency.
Compiled from each provider's current official pages, verified 13 August 2026. Wisp is not an affiliate of The HRT Index.
| Decision factor | Sesame | Hers | Wisp | Winona |
|---|---|---|---|---|
| Published progesterone/progestogen lanes | Micronized progesterone, medroxyprogesterone, fixed combinations; Crinone named | Published menopause kit includes oral progesterone when appropriate | Micronized progesterone, Provera and combination options published | Oral progesterone capsule plus compounded progesterone creams |
| Medication fulfillment | Your local or online pharmacy | Shipped through the program | Your pharmacy; medication separate from care fee | Shipped through Winona or, in some cases, outside pharmacy |
| Care price we can verify here | $59/month standard; $49/month Costco; refill visits from $34 | Confirm during assessment/checkout | $99 for three months of care; medication separate | Oral progesterone currently advertised from $39/month; compounded creams have separate prices |
| Labs included | Five panels if ordered, with state exceptions | Not established on the public menopause page reviewed | No included lab program published on the product page reviewed | No bundled lab program published on the product page reviewed |
| FDA-approved versus compounded | Both may be discussed; must be separated product by product | Published kit names estradiol and oral progesterone; verify the exact dispensed product | Published oral options are FDA-approved finished products | Oral capsule is FDA-approved; final compounded creams are not FDA-approved |
| Peanut-allergy decision | Medroxyprogesterone is peanut-oil-free by label, and Bijuva’s current label does not list peanut oil; product fit still matters | No peanut-free stand-alone progesterone option published on the page reviewed | Provera creates a synthetic peanut-free lane | Provider routes peanut-allergic users toward compounded cream; final cream is not FDA-approved |
Two honest notes belong beside that table.
First, a pending FTC case exists against Hims & Hers. On 29 July 2026, the FTC, Utah and California filed a complaint alleging deceptive billing and cancellation practices and improper sharing of sensitive health information. The case is pending; allegations are not final findings. That does not establish anything about progesterone efficacy, but it is relevant to trust, privacy and cancellation diligence.
Second, Winona markets its compounded cream as peanut-free. Winona also markets it for uterine protection, but the final product is not FDA-approved. That should not be blurred with Bijuva or medroxyprogesterone merely because all three avoid peanut oil.
For deeper provider-specific decisions, see does Wisp prescribe progesterone, does Winona prescribe progesterone and does Hers prescribe progesterone.
What should you ask before booking and during the visit?
A specific question list turns a vague telehealth appointment into a documented prescription decision. The most important items are the exact finished product, whether it contains progesterone or a synthetic progestin, whether it is FDA-approved or compounded, the route and schedule, allergy excipients, refill count, pharmacy cost and what you pay if the clinician declines to prescribe.
Print this. Put it beside the laptop.
Before you book
- Does this clinician's profile specifically mention menopause or HRT?
- Is the clinician licensed and available in my state today?
- Am I booking the menopause subscription or a prescription-refill visit?
- What exact recurring or one-time charge will appear today?
- When is the renewal date, and what is the cancellation deadline?
- Can the prescription go to my preferred pharmacy?
- If no prescription is issued, what charge remains nonrefundable?
During the visit
- What exact product are you prescribing — brand and generic name?
- Is the progestogen progesterone or a synthetic progestin?
- Is the finished product FDA-approved, or is it compounded?
- What strength, route and schedule am I using?
- Does this exact manufacturer's product contain peanut, sesame, soy, corn or another excipient relevant to my allergies?
- Is this use FDA-approved or off-label?
- What bleeding pattern should I expect, and what bleeding needs a call?
- How many refills are authorized?
- What follow-up or testing is required before the next refill?
- What will the pharmacy charge, and does my plan require prior authorization?
The question most people skip is the one that prevents the most anger: “What will I still be charged if you decide not to prescribe?” Ask it before the visit starts if that answer determines whether you book.
What do Sesame patients actually say?
Sesame publishes selected menopause testimonials emphasizing fast access, being heard and local pharmacy pickup. Those quotes are marketing material chosen by Sesame, not independently verified outcomes. They can tell you what parts of the care experience Sesame wants to highlight. They cannot establish that progesterone works, that a prescription is typical or that your experience will match.
The current menopause page includes patient stories about picking up medication from a local Costco within hours and finally finding a clinician willing to discuss the research and the patient's concerns. The useful excerpts are short: “a relief to be helped so quickly” and “go through the research and my concerns.”
Read those as experience signals, not clinical evidence.
- They support the value of quick access and clinician choice.
- They do not prove that a specific patient received progesterone.
- They do not prove symptom improvement from a particular medication.
- Sesame selected the testimonials, so favorable sentiment is built into the sample.
- We could not independently authenticate the patients or verify a progesterone-specific outcome.
That second theme still lands: a provider willing to go through the research and concerns. If you have been dismissed more than once, the product being sold is not only a capsule. It is a conversation you have been trying to have.
What did The HRT Index actually verify?
We directly reviewed Sesame's progesterone, medroxyprogesterone, menopause, refill, Costco and terms pages on 13 August 2026. We checked product ingredients, FDA approval status, labeled uses and dosing against current DailyMed and FDA records. We did not purchase a visit, receive a prescription, test cancellation or verify a clinician's real-time availability.
Verified directly from current provider pages
- Sesame advertises new progesterone prescriptions and refills subject to clinician discretion.
- The menopause page lists progesterone, Prempro, Bijuva and Mimvey.
- Standard menopause care is published at $59/month.
- Eligible Costco members are shown a $49/month women's-health subscription.
- Sesame's own site still contains $54/month menopause teaser cards.
- Prescription-refill visits start at $34, or $29 for Costco members.
- Medication is not included in the subscription price.
- Sesame does not bill insurance for care.
- The five named lab panels and all state exceptions.
- Existing labs may be uploaded and accepted at clinician discretion.
- The first-visit refund language and the 48-hour membership-cancellation rule.
- The Medicare, Medicaid and TRICARE certification restriction.
- Sesame's online controlled-substance exclusion.
Verified against FDA, DailyMed, DEA and peer-reviewed sources
- Current progesterone-only oral capsule labels reviewed list peanut or arachis oil.
- Bijuva contains estradiol plus progesterone and does not list peanut oil in its current inactive ingredients.
- Progesterone injection uses sesame oil and carries the eosinophilic-pneumonia warning.
- Crinone's FDA-approved indications do not include menopausal endometrial protection.
- The labeled cyclic progesterone regimen is 200 mg for 12 days per 28-day cycle with estrogen.
- The February 2026 FDA boxed-warning changes and the retained endometrial warning for systemic estrogen-alone products.
- Testosterone is Schedule III.
- Compounded drugs are not FDA-approved finished products.
- The E3N risk estimates quoted above are observational and do not isolate medroxyprogesterone as a single head-to-head comparator.
- Postmenopausal bleeding requires prompt evaluation and may need imaging or sampling.
Confirm at intake, checkout or the pharmacy
- The exact recurring care price shown to you.
- Whether the $54 teaser price applies to any current checkout path.
- Whether your Costco rate is activated.
- Which clinicians are available in your state and whether they have menopause expertise.
- Which exact product, dose and route your clinician will consider.
- Whether a compounded medication would be offered and which pharmacy would prepare it.
- Your pharmacy's stock, cash price, formulary coverage and prior-authorization rules.
- Whether existing labs are accepted.
- Whether a particular off-label vaginal regimen is appropriate.
Not verified and not claimed
- Any individual clinical outcome.
- That paying for a visit results in a prescription.
- That Sesame will prescribe the product you request.
- That a listed product is currently stocked by your pharmacy.
- That every patient can use online care safely.
We applied The HRT Index Verification Standard: read every published price, separate FDA-approved from compounded, verify state availability and insurance language, and re-check on a fixed schedule — top providers monthly, the full roster quarterly. This page was researched and written by The HRT Index Editorial Team. It is editorial research, not medical advice, and it was not reviewed by a clinician.
Is Sesame a good fit for getting progesterone?
Sesame is a strong fit for a cash-pay woman who values clinician choice, ongoing online care and a prescription sent to her own pharmacy. It is weaker when the visit must be billed to insurance, the medication must be bundled, the exact product must be guaranteed, or symptoms need physical examination or diagnostic testing. The biggest verified strengths are medication breadth and access; the biggest weakness is inconsistent public pricing.
We assess every provider through the same five pillars, in the same order.
Clinical legitimacy
Licensed independent clinicians conduct live video visits and retain prescribing discretion. Prescriptions go to pharmacies rather than bypassing the prescription process. Sesame names reviewers on its own medical pages, but those reviewers did not review this article.
The structural caveat matters: Sesame is a marketplace. Clinicians are independent, and Sesame's own terms say provider listing is not an endorsement. Choose the clinician, do not merely choose the platform.
Care quality
Provider choice is the standout feature. The menopause subscription publishes ongoing video care and messaging rather than a one-form transaction. Five basic lab panels are included if ordered, subject to state exceptions.
The variable is menopause depth. Not every available clinician profile will show the same experience with HRT, complex bleeding histories or off-label routes.
Medication fit
This is Sesame's strongest pillar. It publishes oral micronized progesterone, medroxyprogesterone and multiple fixed estrogen/progestogen products. It also creates more than one allergy fork: medroxyprogesterone for a synthetic route without peanut oil on the label, and Bijuva as an FDA-approved estradiol-plus-progesterone combination whose current label does not list peanut oil when that entire regimen fits.
The gaps are equally clear. Sesame's Prometrium/Crinone wording blurs routes. A product listing is not a guarantee. Compounded treatment must be separated from the FDA-approved finished products every time.
Price transparency
This is the weakest pillar. Sesame currently publishes $59, $54 and $49 menopause figures on different official surfaces. The $34 number is a refill-visit floor and should not be sold as a new-menopause-consult price.
The offsetting strength is structural: medication stays separate and goes to your pharmacy. That preserves the possibility of pharmacy insurance coverage or a discount rather than forcing a single bundled channel.
Access
Sesame advertises same-day appointment availability, local or online pharmacy fulfillment, provider choice and a discounted Costco route. The hard limits are real: federal health-program beneficiaries are excluded under the terms, controlled substances are not prescribed online through Sesame, and actual menopause-clinician availability depends on state and schedule.
Our editorial conclusion
If the thing standing between you and progesterone is access — no timely appointment, no clinician willing to engage, or a refill that needs review — Sesame is one of the more flexible online routes because it combines clinician choice with your own pharmacy.
If the thing standing between you and progesterone is insurance coverage of the visit, a guaranteed exact product, or a symptom that requires imaging, sampling or examination, Sesame is not the answer simply because it is online.
You already know whether you want to do this. You have read enough. The remaining question was never only whether Sesame can prescribe progesterone. It was whether you would be wasting your money finding out.
Now you know what the $34 price actually buys. You know the standard and Costco subscription prices. You know the prescription is not guaranteed. You know why the peanut line matters — and why Bijuva changes the absolute version of that warning. You know which questions force the vague parts into the open before the prescription leaves the clinician's screen.
Choose a Sesame clinician and verify availability in your state (Sponsored link)
Look for menopause or HRT experience, confirm whether you are booking subscription care or a refill visit, and name the exact product you want discussed.
Frequently asked questions
Does Sesame prescribe progesterone?
Yes. Sesame says a provider may write a new progesterone prescription or refill after a live online appointment when clinically appropriate. Payment does not guarantee a prescription, and the product, route, dose and refill quantity remain clinician decisions.
Does Sesame prescribe Prometrium?
Sesame's progesterone page is built around progesterone and Prometrium, and its menopause page names Prometrium. That supports asking for oral micronized progesterone. It does not guarantee brand-name Prometrium rather than a generic.
What progesterone products does Sesame list?
Sesame lists oral micronized progesterone, medroxyprogesterone and combination products including Prempro, Bijuva and Mimvey. It also names Crinone, a vaginal progesterone gel whose approved uses do not include menopausal endometrial protection.
Is Sesame's progesterone FDA-approved?
The FDA-approved finished products discussed on Sesame's pages include micronized progesterone capsules, medroxyprogesterone tablets and combination products. Sesame also says compounded BHRT may be prescribed when deemed appropriate. A compounded finished product is not FDA-approved and must be identified separately.
Does oral progesterone contain peanut oil?
Prometrium and every current US oral micronized progesterone-only capsule label we reviewed list peanut or arachis oil. We found no peanut-free FDA-approved stand-alone oral micronized progesterone capsule. Bijuva is a different product: a fixed estradiol-plus-progesterone capsule whose current inactive-ingredient list does not include peanut oil.
Does progesterone contain sesame oil?
Progesterone injection USP uses sesame oil. Standard oral micronized progesterone-only capsules use peanut or arachis oil instead. Tell the clinician and pharmacist every relevant allergy and verify the exact manufacturer's ingredient list.
How much is Sesame menopause care?
Sesame currently publishes $59/month for standard menopause care and $49/month for eligible Costco members. Some Sesame promotional cards still show $54/month. Verify the live checkout price, recurring term and renewal date.
Is a Sesame progesterone visit really $34?
Sesame advertises prescription-refill visits from $34, or from $29 for Costco members. That is a refill-service floor, not a verified universal price for starting or redesigning menopause HRT.
Is medication included in Sesame's monthly price?
No. Sesame says medication costs are not included. A prescribed product goes to a pharmacy, where the final price depends on the drug, strength, quantity, insurance, prior authorization and discount eligibility.
Can Sesame refill an existing progesterone prescription?
Yes, conditionally. Sesame says refill clinicians typically handle one to two existing prescriptions. Bring the bottle, regimen, indication, pharmacy and recent records. The clinician can approve, change, shorten or decline the refill.
Does Sesame take insurance?
Not for the visit or subscription. Your medication may still be covered at the pharmacy, and outside lab work may be covered depending on your plan.
Can you use HSA or FSA funds?
Sesame's menopause page says most subscription services may be eligible for reimbursement and offers an itemized bill. Its terms say membership fees are not covered under most HSA/FSA plans. Confirm the exact charge with your plan administrator before relying on reimbursement.
Are labs required before Sesame prescribes progesterone?
Not automatically. A clinician may order labs. Five basic panels are included with the subscription when ordered, with direct-payment exceptions in New York, New Jersey, Rhode Island and North Dakota. Existing labs may be uploaded for review.
Can Medicare, Medicaid or TRICARE beneficiaries use Sesame?
No under Sesame's current terms. Users must certify that they are not federal health care program beneficiaries, including Medicare, Medicaid and TRICARE.
Does Sesame prescribe testosterone?
Sesame says its providers do not prescribe controlled substances online. Testosterone is a Schedule III controlled substance and requires a lawful prescription from an appropriately authorized prescriber.
Can Sesame prescribe progesterone without estrogen?
Sesame publishes no simple menopause policy guaranteeing that arrangement. Progesterone and medroxyprogesterone have uses outside menopausal estrogen therapy, so the answer depends on the indication and clinician. Ask directly at intake, and read our guide to taking progesterone without estrogen.
What if the clinician will not prescribe it?
Sesame's refill page says a visit is not refundable merely because the clinician decides a prescription is unnecessary. For the menopause subscription, cancelling at least three hours before the initial visit currently qualifies for a full refund; after the visit occurs, the first month is not refunded.
Can you cancel the Sesame subscription anytime?
You can request cancellation, but timing controls the next charge. Sesame's terms require cancellation at least 48 hours before the renewal processing date and do not provide a prorated refund for the current term. Set a reminder 72 hours before renewal.
What should you do about postmenopausal bleeding?
Arrange prompt clinical evaluation. Telehealth may help triage and coordinate care, but the evaluation may require transvaginal ultrasound, endometrial sampling or other testing. Do not treat unexplained postmenopausal bleeding as a routine refill issue.
Primary sources used for this verification
- Sesame progesterone prescribing page
- Sesame menopause treatment page
- Sesame online prescription-refill visit page
- Sesame medroxyprogesterone page
- Sesame Costco membership-perks page
- Sesame Terms of Service
- DailyMed: progesterone capsules
- DailyMed: Bijuva label
- DailyMed: Crinone label
- FDA menopause guidance
- FDA 2026 menopausal hormone therapy labeling changes
- FDA: Understanding the risks of compounded drugs
- DEA drug scheduling
- The Menopause Society: Hormone Therapy
- E3N cohort study on breast-cancer risk by progestogen
- ACOG 2026 update on postmenopausal bleeding evaluation
- Hers menopause program
- Wisp menopause consult
- Winona progesterone capsules
- FTC pending Hims & Hers case
Still not sure which HRT program is right for you? Take our free 60-second matching quiz.
This page provides editorial research and general information. It is not medical advice and has not been reviewed by a clinician. Prices, policies, formularies and labels change. Talk with a licensed clinician before starting, stopping or changing hormone therapy.