Prometrium Online Prescription: The Safest Ways to Get Progesterone Capsules
By The HRT Index Editorial Research Team · · Educational only — not medical advice · Affiliate disclosure · Privacy policy
The HRT Index does not prescribe, sell, or dispense Prometrium. We earn a commission if you start care through some of the links below, at no extra cost to you — that never changes what we verify or who we recommend.
If you want a Prometrium online prescription, here’s the short version: yes, you can get one. A licensed clinician reviews your health online and, if progesterone is right for you, sends the prescription to a pharmacy near you — often for same-day pickup — or to a mail pharmacy for delivery. Progesterone is prescription-only, so skip any website that offers it without a visit.
The best route depends on your situation. Sesame is the simplest way to get a new prescription or a refill. Midi is best if you want insurance to help pay. Winona and Hers ship a full menopause plan to your door for cash.
Two things almost no one tells you upfront
- The generic is the same FDA-approved medicine. Drugs.com lists brand Prometrium from about $497 for 30 capsules, while the generic starts around $12–$15 for the same 30.
- A valid prescription doesn’t guarantee your pharmacy has it in stock.Progesterone capsules have been on the national shortage list since 2023. We’ll show you how to handle both.
The 30-second answer
Prometrium is a brand-name oral micronized progesterone capsule — a bioidentical progesterone, meaning it’s chemically identical to the hormone your body makes. You can get it online only after a licensed clinician reviews your history and decides it’s appropriate; the prescription then goes to a pharmacy for pickup or delivery. A cheaper FDA-approved generic is available. It is prescription-only — there is no legitimate over-the-counter version.
This page is for you if:
- You’ve been told to add progesterone to your estrogen, or you’re starting both.
- Your Prometrium prescription ran out and you want a refill without a long wait.
- You want to compare same-day pickup, shipped plans, insurance, and cash prices before you pay.
Not the full answer for you if:
- You have a peanut allergy (capsules contain peanut oil — see peanut-free options below).
- You have unexplained vaginal bleeding, a history of breast or reproductive cancer, blood clots, stroke, heart attack, or liver disease, without clinician guidance yet.
- You need emergency care.
Start here: which route fits you?
| If this sounds like you | Start with | Why |
|---|---|---|
| “I just need the prescription (or a refill), and I want it simple.” | Sesame | Same-day online visit; a clinician can send a new prescription or a refill to your local pharmacy or ship it. |
| “I want insurance to help pay, or a menopause specialist to manage my whole plan.” | Midi | In-network with most PPO plans; menopause-trained clinicians prescribe FDA-approved progesterone. |
| “I want everything — estrogen and progesterone — shipped to me for cash.” | Winona or Hers | Full menopause plans by mail. (Read the Winona label note below first.) |
| “I already have a valid prescription.” | Your pharmacy + a discount card | You may not need another visit. Compare cash price and stock first. |
| “I have a safety flag, or I’m not sure what I need.” | An in-person clinician or our quiz | Some situations need hands-on care first. |
A prescription is written only if it’s clinically right for you.
Is a Prometrium online prescription legal and safe?
Yes — as long as a licensed clinician reviews your health and decides progesterone is appropriate. Prometrium is not sold over the counter. The legal online path is simple: you complete an intake, a clinician reviews it (by video or secure questionnaire), and if it’s a fit, they send the prescription to a pharmacy. Any site offering Prometrium with no clinician and no prescription is a red flag — treat it as a safety risk, not a shortcut.
Here’s the whole process, start to finish:
- Pick a licensed online provider. (We compare the main ones below.)
- Complete your intake. You’ll answer questions about your symptoms, health history, whether you have a uterus, and any medications.
- Get reviewed. A clinician looks it over. Some do a live video visit; some review your answers and message you.
- If approved, your prescription is sent to a local pharmacy for pickup, or shipped to your home.
What Prometrium is actually approved for
According to the FDA-approved Prometrium label, it’s indicated to prevent endometrial hyperplasia — an overgrowth of the uterine lining that can raise cancer risk — in women who still have a uterus and take estrogen. It’s also approved for secondary amenorrhea (missed periods not caused by pregnancy). In plain terms: if you take estrogen and still have your uterus, progesterone protects that lining.
Your 3-part “is this legit?” filter
A trustworthy online service will always do all three. If even one is missing, walk away.
- A real clinician reviews you before anything is prescribed.
- A real pharmacy fills it — you can see where it’s going.
- The product is prescription-only — no “no prescription needed” claims.
The fastest, simplest ways to get Prometrium online (compared)
For most people, Sesame is the simplest way to get a new prescription or refill, and Midi is the best choice if you want insurance to help pay.The table below is our hand-checked comparison of every realistic route — what each one actually gives you, whether it’s FDA-approved, whether you can get progesterone by itself, what it costs, and how we verified each claim.
We call this The Prometrium Online Prescription Route Matrix.The last column tells you exactly how solid each row is — a fact confirmed on a public page, a number the provider states, or something to confirm at checkout.
| Route | New online prescription? | FDA-approved capsule path? | Progesterone by itself? | Uses insurance? | Typical cash cost (visit + medicine) | How we verified |
|---|---|---|---|---|---|---|
| Sesame | Yes — new or refill, if a clinician approves | Yes — clinician sends FDA-approved brand or generic to your pharmacy | Yes | No (HSA/FSA; gives receipts to submit) | Visit ~$19–$37 (shown upfront) + generic (~$14 with coupon) | Verified on Sesame’s pages; med price is checkout-dependent |
| Midi | Yes, as part of menopause care | Yes — FDA-approved progesterone to an outside pharmacy | Yes (clinician decides) | Yes — in-network with most PPOs | ~$250 first visit / ~$150 follow-up cash; medicine billed separately | Verified on Midi’s pages |
| Winona | Yes, after online evaluation | ⚠ Capsule is provider-stated FDA-approved (see note below) | Usually part of a plan, not alone | No (HSA/FSA) | Capsule from ~$39/mo + visit | Provider-stated; FDA status not independently verified by us |
| Hers | Yes, if eligible | Oral progesterone when a provider approves | No — for women already on estrogen | No | Oral hormones from ~$79/mo (annual plan) | Provider-stated; confirm price at checkout |
| Your pharmacy + discount card (existing prescription) | No — fills an existing prescription | Yes — pharmacy dispenses FDA-approved brand or generic | Yes | Coupon or cash | Generic from ~$12–$15 for 30 capsules | Verified on GoodRx and Drugs.com |
Our take for this search
If you want speed, a refill, or progesterone by itself, start with Sesame. If you want insurance to help or a menopause specialist to manage your full plan, start with Midi. Consider Winona or Hersif you’d rather have your whole plan shipped in one box for cash — and ask Winona to confirm its capsule’s FDA status before you pay. We don’t crown Winona the winner here, because Winona’s own pages don’t fully resolve whether its capsules are FDA-approved or compounded.
Which route is right for you?
Match your situation to a route below. Each one solves a different problem, so pick the line that sounds like you.
You have insurance and want it to help pay → Midi.It’s in-network with most PPO plans and prescribes FDA-approved progesterone. Note: Midi is not in-network with Medicaid or Medi-Cal, and Medicare members can only use it as self-pay.
You want it fast, or just a refill → Sesame. A clinician can write a new prescription or refill an old one and send it to your local pharmacy. Cash-pay, with prices shown before you book.
You want your full menopause plan shipped for cash → Winona or Hers. Convenient, discreet, HSA/FSA-friendly. Read the Winona note in the next section first.
You already have a valid prescription → skip the visit. Fill the generic at your pharmacy with a discount card. The price math is in the cost section below.
You have a safety flag, or you’re just not sure →don’t rush an online refill.
Brand Prometrium vs generic vs compounded — and the money-saving truth
Brand Prometrium and generic micronized progesterone are the same FDA-approved medicine, in the way that matters: the same active ingredient, at the same strength, rated therapeutically equivalent by the FDA. Compounded progesterone is a different category and is not FDA-approved.
Prometrium (brand)
FDA-approved oral micronized progesterone capsule made by Virtus Pharmaceuticals, 100 mg and 200 mg strengths.
Generic micronized progesterone
Same active ingredient. FDA’s AB rating means therapeutically equivalent — a pharmacist can swap it unless your doctor writes “brand only.” Inactive ingredients can differ.
Compounded progesterone
Custom formula mixed by a compounding pharmacy. Not FDA-approved as a finished product. Not equivalent to, safer than, or more natural than FDA-approved options.
Cash price benchmark —
| Product (30 capsules) | Cash price benchmark |
|---|---|
| Generic progesterone, 100 mg | From about $11.77 (Drugs.com); as low as $14.10 with a free GoodRx coupon |
| Generic progesterone, 200 mg | From about $17.54 (Drugs.com) |
| Brand Prometrium, 100 mg | From about $496.54 (Drugs.com) |
| Brand Prometrium, 200 mg | From about $936.14 (Drugs.com) |
Sources: Drugs.com price guide; GoodRx, verified July 2026. Prices vary by pharmacy, dose, and coupon.
The honest thing we’ll say that might cost us a click
If you already have a doctor who will write the prescription, the cheapest way to get this medicine is nota paid telehealth visit — it’s a generic fill at your own pharmacy for around $14. A cash membership can’t beat a $14 generic on the pill price alone. But if you don’thave a prescriber, need it soon, want a menopause specialist to manage your dose and estrogen too, or your pharmacy is out — then the visit fee buys you real clinical help and convenience. The pill is cheap; the accessis what you’re paying for.
Sesame — best for a fast prescription or a refill
Sesame is the strongest fit when your goal is speed, a low price, or a refill you can pick up locally. You choose a provider, do a video visit, and if progesterone is appropriate they send a new prescription — or refill your old one — to a nearby pharmacy or an online pharmacy for delivery.
What makes Sesame work for this search:
- New prescriptions and refills, sent to the pharmacy you pick — including local pickup.
- Cash-pay, no insurance games. Sesame doesn’t bill insurance, but it accepts HSA/FSA cards and gives you receipts to submit to your plan.
- Prices shown upfront. Cash visits typically run about $19–$37 depending on the provider and visit type, so you know the cost before you book. (There’s also a $99/month menopause subscription, but you don’t need it just to get a progesterone prescription — a single visit works.)
- Cheap generics. Sesame’s own pharmacy, SesameRx, offers many generics for $5 with free delivery nationwide; whether your specific progesterone qualifies depends on the medication and how it’s written — check at checkout.
- It can prescribe progesterone by itself — you don’t have to sign up for a full estrogen plan to get it. That’s the piece Winona and Hers don’t offer.
The one trade-off, stated plainly
Sesame does not run an insurance-billed menopause specialty clinic that manages your entire hormone plan for you. If you want that, Midi is the better fit.But because Sesame skips the specialty-clinic model, it stays simple and cheap — which is exactly why it wins for a fast prescription or refill.
“I saw Michele for perimenopause HRT and she was very helpful… I was able to pick them up from my local Costco in a few hours.”
Provider-published testimonial on Sesame’s own site. Reflects one person’s experience — not a guarantee of prescribing, results, or pharmacy stock, and not a claim about how the medicine performs.
Midi — best if you want insurance to help pay
Midi is the stronger route when Prometrium is part of a bigger menopause plan, or when you want insurance to cover the visit.Midi’s clinicians specialize in midlife women’s health, and they prescribe FDA-approved oral micronized progesterone — the same medicine as Prometrium — to your pharmacy.
What makes Midi work for this search:
- In-network with most PPO plans, in all 50 states. Your visit is billed like a specialist copay.
- Cash prices are published too: around $250 for the first visit and $150 for follow-ups if you don’t use insurance. Medicine and any labs are billed separately.
- Menopause-trained clinicians who can manage your estrogen, your dose, and your progesterone together.
- Important: Midi is not in-network with Medicaid or Medi-Cal, and it’s not covered by Medicare (Medicare members can use it as self-pay only).
One distinction to keep straight (this matters)
Midi does two separate things with progesterone. Its clinicians can prescribe FDA-approvedoral micronized progesterone that you fill at a pharmacy — that’s the Prometrium-equivalent route. Midi also sells its own compoundedprogesterone product, shipped from its pharmacy, which is peanut-free and vegan — a different, non-FDA-approved category. If FDA-approved is what you want, ask specifically for the FDA-approved capsule sent to your pharmacy, and confirm the price of any compounded option at checkout.
“Midi was so easy: I got a same day appointment and they took my insurance.”
Published on Midi’s own site. One person’s experience — not a guarantee of coverage, prescribing, or outcomes.
Winona and Hers — for a full plan shipped to your door
Winona and Hers make sense if you want your whole menopause plan — estrogen and progesterone — shipped to you for cash, rather than picking up a single prescription.They’re convenient and discreet, but neither is the cleanest first answer for someone specifically searching for a Prometrium prescription. Read the details before you decide.
Winona
Winona ships bioidentical hormone plans and can include a progesterone capsule from about $39/month, with HSA/FSA accepted and free shipping in roughly 5 business days. Its capsules contain peanut oil, so they’re off-limits if you have a peanut allergy (Winona’s progesterone cream is peanut-free, but the cream is compounded, and we don’t treat it as a Prometrium-equivalent).
The note we owe you on Winona
Winona’s product page and FAQ describe its progesterone capsules as FDA-approved, while other Winona pages state that Winona owns and operates 503A compounding pharmacies and that its compounded treatments are not FDA-approved. Because those statements sit uneasily together, we treat the capsule as provider-stated FDA-approved — not independently verified by The HRT Index— until the exact dispensed product’s manufacturer or FDA-approved status is documented.
If a shipped Winona plan appeals to you, ask directly: is the exact capsule you’ll dispense to me an FDA-approved brand or generic, or a compounded capsule? Get the answer before you pay.
Hers
Hers offers online menopause and perimenopause care, and its plans can include oral progesterone when a provider decides it’s appropriate — but progesterone at Hers is meant for women already taking estrogen, not as a standalone. Oral hormone plans start around $79/month on an annual plan; confirm the current price and the exact product at checkout. Hers is not available in all 50 states. One honest note from Hers itself: hormone therapy is not FDA-approved specifically for perimenopause, though clinicians may prescribe it off-label at their discretion.
Not sure whether you need progesterone alone, a full plan, or something else?
Take the Find My HRT Path match before choosing a provider. It’ll point you to the right fit for your symptoms and your state.
Find My HRT Path →How much does Prometrium cost online without insurance?
Your total has two parts: the clinician visit (or subscription) plus the medicine at the pharmacy. The generic is usually far cheaper than the brand — often around $14 for 30 capsules versus several hundred dollars for brand Prometrium.Don’t compare providers on visit price alone.
| Cost piece | What to check | Current benchmark |
|---|---|---|
| Online visit or subscription | Visit fee, membership, refill policy | Sesame visit ~$19–$37 (shown upfront); menopause subscription ~$99/mo |
| Generic progesterone capsule | Strength, quantity, pharmacy, coupon | From about $11.77 for 30 capsules (Drugs.com); as low as $14.10 with a GoodRx coupon |
| Brand Prometrium | Brand vs generic, stock, prior authorization | From about $496.54 for 30 100 mg capsules (Drugs.com) — verify at your pharmacy |
| Midi visits | Insurance or self-pay | ~$250 first visit / ~$150 follow-up self-pay; medicine and labs billed separately |
| Winona capsule | Monthly plan price | From ~$39/mo (confirm the capsule’s FDA status first) |
The takeaway: the expensive part of getting Prometrium online is usually the visit, not the pill. If you can get the visit covered (Midi) or cheap (Sesame), then fill the generic, you’ll pay far less than brand-name cash pricing. See our full HRT cost guide for a broader breakdown, or our HRT insurance coverage guide if you want the insurance deep-dive.
The progesterone shortage — will your pharmacy even have it?
A valid prescription doesn’t guarantee your pharmacy has Prometrium in stock. Progesterone capsules — brand and generic — have been on the ASHP national drug shortage list since 2023, and availability still varies by pharmacy and region in 2026.This is the piece that trips people up: they do everything right online, then hear “we don’t have it.” Here’s how to get ahead of it.
What’s actually happening — ASHP data, verified July 2026
- ASHP shortage entry created December 5, 2023; last updated October 1, 2025.
- Amneal (a generic maker) reports its capsules available; Virtus reports brand Prometrium (100 mg and 200 mg) available — but supply has been intermittent. Aurobindo has not provided availability information.
- Both 100 mg and 200 mg strengths have been affected at different times.
- It’s regional and rotating. A pharmacy may have it one week and not the next. Independent pharmacies often source it when big chains can’t.
- Why now: demand for menopause hormone therapy has climbed sharply, and progesterone demand rises right alongside estrogen. With only a few manufacturers, a single hiccup ripples nationwide.
Your shortage game plan — do these beforeyou’re out:
- Ask your clinician to write “progesterone capsules,” not “Prometrium.” That lets the pharmacist dispense whichever manufacturer’s FDA-approved product is in stock. Writing brand-only (“dispense as written”) narrows your options.
- Ask for a 90-day supply when you find it in stock, so you navigate the shortage less often. Confirm your plan allows 90-day retail fills.
- Call more than one pharmacy— including a local independent — and ask which manufacturer and strength they have.
- Ask your clinician about a backup.If micronized progesterone isn’t available, ask your prescriber whether an established alternative such as medroxyprogesterone acetate is appropriate for you. That’s a conversation for your clinician, not a swap to make on your own.
- Never stretch, skip, or split doseswithout your clinician’s okay. If you take estrogen and still have a uterus, gaps in progesterone can raise the risk to your uterine lining.
Because stock is local and rotating, the smartest move is a prescription you can direct to a specific pharmacy you’ve already confirmed has it.
Who should not get Prometrium online without more care
Some situations need hands-on evaluation before you start or refill progesterone — this is not a simple online refill for everyone. According to the FDA-approved Prometrium label, the medicine should not be used by people with the following, unless a clinician who knows their full history says otherwise.
| Red flag | Why it matters |
|---|---|
| Peanut allergy | Prometrium capsules contain peanut oil and should never be used by anyone allergic to peanuts. |
| Unexplained vaginal bleeding | Bleeding that hasn’t been checked needs evaluation before hormones. |
| Known, suspected, or past breast cancer | Listed as a contraindication on the label. |
| Known or suspected cancer of the reproductive organs | Listed on the patient label as a reason not to use without clinician direction. |
| Blood clots (DVT or PE), now or in the past | Listed as a contraindication. |
| Recent stroke or heart attack | Active or recent arterial clot-related disease is a contraindication. |
| Liver problems or liver disease | Listed as a contraindication. |
| Known or suspected pregnancy | Prometrium is not for use in pregnancy for this purpose. |
Peanut allergy? You still have options.
Prometrium contains peanut oil, and many oral progesterone capsules do too — so check the exact product’s inactive ingredients before you fill. Peanut-free routes a clinician might consider, depending on why you need progesterone, include a progesterone vaginal insert (such as Endometrin), a vaginal gel (such as Crinone), or a compounded peanut-free form (clearly a compounded product, not FDA-approved-equivalent). Bring the allergy up at the start of your visit so your clinician can plan around it.
What to have ready before your visit
A good online clinician will ask enough to decide whether progesterone is safe and right for you. Having your answers ready makes the visit faster and helps your clinician decide safely.
Have these ready:
- Do you still have a uterus? (This drives whether — and why — you need progesterone.)
- Are you taking systemic estrogen, and in what form (patch, pill, gel, spray, or vaginal only)?
- Are you postmenopausal, perimenopausal, or using progesterone for missed periods?
- Any abnormal bleeding lately?
- Any peanut allergy?
- Any history of blood clots, stroke, heart attack, liver disease, or breast cancer?
- What medications and supplements do you take? (Flag anti-seizure meds, certain antibiotics, and St. John’s Wort — they can interact.)
- Do you want local pickup or home delivery?
- Do you prefer brand Prometrium or the generic? (The generic is the same FDA-approved medicine and usually far cheaper.)
- Do you need insurance billing, HSA/FSA, or cash pricing?
How we verified this
We built this page under The HRT Index Verification Standard: read every published price and policy, separate FDA-approved products from compounded ones, check state availability and insurance, and re-verify on a fixed schedule. We rate providers on five things, in this order: clinical legitimacy, care quality, medication fit, price transparency, and access.
Verified from a public source —
- The FDA-approved Prometrium label — indications and contraindications.
- ASHP drug shortage entry for progesterone capsules (created December 2023; updated October 2025), including manufacturer stock status.
- Sesame’s online progesterone route (new prescriptions and refills, local pickup, SesameRx generics) and its upfront cash-visit pricing.
- Midi’s PPO in-network status and self-pay visit pricing, and its separate FDA-approved vs compounded progesterone routes.
- GoodRx and Drugs.com pricing for generic and brand progesterone.
Provider-stated (we report it, but haven’t independently confirmed):
- Winona’s claim that its progesterone capsule is FDA-approved.
- Hers’s inclusion of oral progesterone in its plans.
Still worth a checkout-day check:
- The exact price you’ll see at Sesame checkout and in your state.
- Whether a Winona capsule dispensed to you is FDA-approved or compounded.
- Current pharmacy stock and today’s coupon price for your ZIP code.
Pricing, availability, insurance, pharmacy stock, and provider policies change — that’s why we date everything and re-check on a schedule.
Frequently asked questions
- Can I get a Prometrium online prescription?
- Yes. A licensed clinician reviews your health online and, if progesterone is appropriate, sends the prescription to a local or online pharmacy — often the same day for local pickup. It cannot be sold without that review.
- Can I buy Prometrium without a prescription?
- No. Prometrium and generic progesterone capsules are prescription-only. Any site offering them with no clinician review should be treated as a safety risk.
- Is generic progesterone the same as Prometrium?
- In the way that matters, yes. Generic micronized progesterone has the same active ingredient at the same strength and is rated therapeutically equivalent to brand Prometrium by the FDA, so a pharmacist can substitute it unless your doctor writes brand only. Inactive ingredients can differ, and the generic is usually far cheaper.
- Is compounded progesterone the same as Prometrium?
- No. Compounded progesterone is a custom formula that is not FDA-approved as a finished product, and should not be described as equivalent to, safer than, or more natural than FDA-approved Prometrium or its generic.
- Does Prometrium contain peanut oil?
- Yes. The Prometrium label states the capsules contain peanut oil and should never be used by anyone allergic to peanuts. Many generic capsules do too, so check the exact product. Peanut-free routes a clinician might consider include a vaginal insert (Endometrin), a vaginal gel (Crinone), or a compounded peanut-free form.
- Can an online doctor send Prometrium to CVS, Walgreens, or Costco?
- Usually yes, depending on the provider and your state. Sesame, for example, sends approved prescriptions to a local or online pharmacy you choose.
- How much does Prometrium cost without insurance?
- The generic starts around $12–$15 for 30 capsules, and as low as $14.10 with a GoodRx coupon. Brand Prometrium is far more — Drugs.com lists it from about $496.54 for 30 100 mg capsules. Your total also includes the visit fee, which varies by provider.
- Is Prometrium in shortage right now?
- Progesterone capsules have been on the ASHP drug shortage list since 2023, with the entry last updated in October 2025. Some manufacturers report stock, but availability varies by pharmacy and region, so call ahead.
- Do I need progesterone if I don’t have a uterus?
- Often not for endometrial protection, since there’s no uterine lining to protect. But a clinician may still prescribe it for other reasons. This is a decision to make with your provider based on your anatomy and plan.
- What if my pharmacy is out of stock?
- Ask about other manufacturers and strengths, call an independent pharmacy, and ask your prescriber about a 90-day fill or an established alternative. Don’t change your dose on your own.
- What’s the fastest way to get a Prometrium prescription online?
- For a same-day prescription or refill with local pickup, Sesame is the strongest route. For insurance-covered specialist care, Midi is the stronger choice.
Still deciding?
Getting progesterone online is straightforward once you know your route. If you want it fast or simple, Sesame can write a new prescription or refill and send it to your pharmacy. If you want insurance to help, Midiprescribes the FDA-approved medicine and bills most PPO plans. If you’d rather have a full plan shipped, look at Winona or Hers— and ask Winona to confirm its capsule’s FDA status first.
Still not sure which HRT program is right for you? Take our free matching quiz.
Related from The HRT Index
- Sesame HRT review — same-day cash visits, plain-English breakdown
- Midi Health review — insurance-covered menopause specialist care
- FDA-approved vs compounded HRT: what’s the difference?
- How much does HRT cost? 2026 guide
- HRT insurance coverage — PPO, HSA, FSA, Medicare, Medicaid
- Menopause medications list 2026 — every category, hormonal and non-hormonal
- Estradiol prescription online — the companion guide to getting estrogen
- Which online HRT providers prescribe what — form-by-form prescribing map
- FDA-approved HRT medication list 2026 — full reference by type and route
- HRT benefits and risks — updated for 2026
Sources — verified July 2026
- FDA-approved Prometrium (progesterone) label — indications, contraindications, peanut oil, dosing. U.S. FDA / DailyMed. accessdata.fda.gov and dailymed.nlm.nih.gov
- ASHP Drug Shortage database — Progesterone Capsules (created Dec 5, 2023; updated Oct 1, 2025; Amneal and Virtus/Prometrium available, Aurobindo not providing information). ashp.org/drug-shortages
- GoodRx — progesterone/Prometrium 2026 prices and coupons (generic as low as $14.10; updated June 2026). goodrx.com/progesterone
- Drugs.com — Prometrium and progesterone price guides (generic 100 mg from $11.77 / 200 mg from $17.54 per 30; brand 100 mg from $496.54 / 200 mg from $936.14 per 30). drugs.com/price-guide
- Sesame — online progesterone (Prometrium) prescription page, prescription-refill visit pricing, and SesameRx $5 generics. sesamecare.com
- Midi Health — HRT, pricing & insurance, and Custom Rx progesterone pages. joinmidi.com
- Winona — progesterone capsule product page and HRT/FDA-status statements. bywinona.com
- Hers — menopause and perimenopause care pages (oral progesterone, pricing, state availability). forhers.com
- FDA — Orange Book / therapeutic equivalence (AB-rated generics) and compounding Q&A (compounded drugs are not FDA-approved). fda.gov
- The North American Menopause Society (The Menopause Society) — 2022 Hormone Therapy Position Statement (progestogen required with estrogen for endometrial protection; micronized progesterone). menopause.org
By The HRT Index Editorial Research Team. Educational research only — not medical advice, and not reviewed by a clinician. FDA-approved and compounded options are labeled distinctly throughout; compounded progesterone is never implied to be equivalent to, safer than, or more natural than FDA-approved medication. Because our Find My HRT Path tool collects sensitive health information, we handle it under our consumer-health-data and privacy policy. See our affiliate disclosure.