Duavee Cost Without Insurance: What You’ll Actually Pay in 2026

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Duavee cost without insurance runs about $194 to $267 for 30 tablets across current cash and coupon prices. But a Pfizer-supported price on the federal TrumpRx site was $30.30for the same quantity on July 28, 2026, and qualifying patients may get it free through Pfizer assistance. The advertised “$25” card? Commercially insured women only.

⚠️ First, a correction — because it matters

If you searched this question recently, you may have read that Duavee costs $300 to $500 a month without insurance.

We checked. That’s not what we found.

Every current price source we looked at on July 28, 2026 landed between the $30.30 Pfizer-supported offer on TrumpRx and a $267.44 average cash price at SingleCare. Not one was above $270.

We’re telling you this in the first 200 words because we know what a wrong number does. You read $400 a month, you do the math, and you decide you can’t have the medication your doctor just prescribed. That decision gets made at a pharmacy counter, quietly, by women who never find out they had other options.

You have other options. Here they are.

The four ways to pay, side by side

These are four different payment routes, not four quotes for the same thing. Which one applies to you depends on your insurance status and your income — and that’s the whole game.

Prices captured July 28, 2026 from TrumpRx, SingleCare, and Drugs.com. Twelve-fill figures are simple planning math, not a guarantee. Confirm your price with your pharmacy before filling.

One important note on that SingleCare row. SingleCare currently displays $191.11, but that price includes a one-time $3 signup credit for new members. The recurring price — what you’d pay every month after the first — is $194.11. A first year of one $191.11 fill plus eleven $194.11 fills comes to $2,326.32.

We’re being fussy about this because that $3 is the difference between an honest annual number and a marketing one, and you’re the person who has to live inside the annual number.

The gap between the TrumpRx route and a $206.04 cash benchmark is about $175.74 per fill — $2,108.88 across twelve fills. Same drug. Same quantity. Different payment route.

Is this page for you?

Yes, if:

• You’ve been prescribed Duavee and have no prescription coverage
• You have insurance but it won’t cover Duavee, or your deductible means you’re paying cash anyway
• The pharmacy quoted you a number that made your stomach drop
• You want to know the difference between a coupon, a savings card, and patient assistance — because they’re three different things with three different rulebooks

What we actually verified

You shouldn’t trust a single number above without knowing where it came from.

If a page tells you a price and won’t tell you how it got it, treat it the way you’d treat a stranger’s stock tip.

How much does Duavee cost without insurance in 2026?

Duavee’s cash price for 30 tablets runs from about $194 with a recurring discount coupon to $267.44 as a published average cash price. A Pfizer-supported self-pay price of $30.30 for the same quantity appeared on the federal TrumpRx platform and on GoodRx as of July 28, 2026. No FDA-approved generic version of Duavee was identified, so no lower-cost version of the identical medication exists.

Here’s every source we checked, and what each number actually measures. That second part matters more than you’d think.

These sources aren’t measuring the same thing

Look again. The same 30 tablets get described as $202.00, $206.04, $249.18, and $267.44.

That’s not four sites disagreeing about one fact. It’s four sites publishing four different statistics. TrumpRx calls $202 its original price. Drugs.com publishes a cash benchmark. GoodRx publishes an average retail figure. SingleCare publishes an average cash price.

Nobody explains that. Everyone picks one number, calls it “the price,” and moves on.

So here’s the habit worth keeping — for this prescription and every one after it. When you see a drug price online, ask which of these five it is:

1. Average or benchmark cash price — a statistic, not your quote
2. Recurring coupon price — what a discount card gets you every month
3. First-fill promotion — a signup bonus or trial credit, once only
4. Manufacturer-supported self-pay price — negotiated, with its own terms
5. Assistance price — free or reduced, but you apply and qualify

All five are on this page. Once you can tell them apart, prescription pricing stops feeling random and starts feeling navigable.

What Duavee costs over a year

Duavee is one tablet daily, so 30 tablets is a 30-day supply.

• TrumpRx self-pay route: $363.60 a year
• SingleCare recurring coupon: $2,329.32 a year
• At a $249.18 average retail figure: $2,990.16 a year

The distance between the first and third line is $2,626.56. That’s not a rounding error. That’s a used car.

Why does Duavee cost $30 one way and $250 another?

Duavee has four separate payment programs, each with its own eligibility rules, and they are routinely described as though they were interchangeable. The “as little as $25” savings card is limited to commercially insured patients. The $30.30 price is a manufacturer-supported self-pay offer. Patient assistance is income-based, for uninsured and government-insured patients. Published cash prices apply when none of the others are used.

This is the part most pages get wrong, and it’s why so many women conclude there’s nothing out there for them.

Find your row.

Now look at the two Pfizer rows.

They’re mirror images. The savings card takes commercially insured women and turns away everyone else — Pfizer’s own terms exclude cash-paying patients and state and federal healthcare program beneficiaries. Patient assistance does the reverse: uninsured and government-insured women qualify, commercially insured women don’t.

If you’re uninsured, the discount advertised everywhere — the “$25” one, the one on the savings-tips pages — is structurally unavailable to you. Not because you did something wrong. Because that’s how it was built.

That’s almost certainly why you kept hitting a wall. You weren’t looking in the wrong places. You were being shown a door that was locked for you specifically.

The two doors that open are next.

Is the $30.30 Duavee price real, and how do you use it?

The $30.30 figure is a Pfizer-supported self-pay price listed on TrumpRx, a federal website that publishes cash prices negotiated with drug manufacturers. It is not insurance and not a pharmacy — it issues a coupon you present at a participating pharmacy. The listing was observed on July 28, 2026 and should be rechecked before filling.

We went and looked. Here’s exactly what the page showed.

What’s on the page

Duavee, listed under Pfizer, tablet form, 0.45/20 strength. Set quantity to 30 and you get:

• Original price: $202.00
• Savings: −$171.70
• TrumpRx price: $30.30
• Labeled 85% off

The coupon carries the routing details your pharmacist needs: BIN 015995 · PCN GDC · Group MAHA · Member ID TRUMPRX. The page says the offer is widely supported at retail pharmacies that dispense Duavee.

What TrumpRx is

TrumpRx launched in February 2026 as a federal platform publishing cash prices negotiated between the government and drug manufacturers, including Pfizer. You can’t buy anything on the site. It gives you a coupon, or sends you to a manufacturer’s own storefront.

GoodRx currently displays the same Pfizer-sponsored $30.30 offer. To be clear about what that means: it’s one offer showing in two windows, not two separate deals. “Two sources agree” would sound stronger than the truth supports, so we’re not saying it.

Three things to know before you go

Participation isn’t universal. The offer page doesn’t list which pharmacies accept it. Confirm participation and the final processed price before anything is dispensed.

Government coverage is unresolved on this offer. The public Duavee page doesn’t display complete eligibility terms for Medicare, Medicaid, VA, or TRICARE enrollees. If you have any of those, read the coupon’s terms first. Separately — and this part is official — Medicare notes that a cash purchase made outside your Part D plan doesn’t count toward your Part D deductible or out-of-pocket maximum.

Check state-specific restrictions in the coupon’s terms. Some prescription coupons carry them.

Can you get Duavee for free without insurance?

Yes, if you qualify. Duavee is included in Pfizer’s 2026 Patient Assistance Program, which provides medication at no cost to uninsured and government-insured patients whose annual pre-tax household income is at or below 300% of the federal poverty level. Commercially insured patients are not eligible. Approval is not automatic — an application is required, and your prescriber must complete part of it.

Before the paperwork, something worth reading.

“I quit taking it last week. My insurance quit paying for it.”

— Duavee user of nearly three years, WebMD review page (retrieved July 28, 2026)

We didn’t write that. We’re not going to dress it up. That’s a woman who stopped a medication because of money and posted about it in a drug review box because there was nowhere else to put it.

If that’s roughly where you are: this is the section that matters most on this page.

The income limits

The federal poverty level (FPL) is an annual income figure published by the government and used to decide who qualifies for assistance. Below are Pfizer’s published 2026 figures — 300% of FPL, by household size.

Pfizer Patient Assistance Program, 2026. Pfizer makes the final decision — this table is a screen, not an approval.

Read that table again if you skimmed it.

A household of two under about $65,000 qualifies for the screen. A household of four under $99,000 qualifies. A lot of women see “patient assistance” and picture a program for people in crisis. These are ordinary middle-class incomes. If you’re anywhere near these numbers, apply. The worst outcome is a no, and it costs you nothing to find out.

What the application involves

We’d rather you know the friction now than discover it halfway through.

• Your prescriber has to sign it. There’s a section only they can complete. You can’t file alone.
• You’ll need proof of income — a recent tax return, W-2s, or pay stubs. Fill in everything.
• If you’re on Medicare Part D or Medicare Advantage: for 2026, Pfizer requires you to enroll in the voluntary Medicare Prescription Payment Plan before requesting assistance, and to provide documentation. Pfizer may also require you to seek and document a denial from other applicable funding resources first.
• You must be uninsured or government-insured. Commercial insurance — including through a job or a federal employer plan — makes you ineligible for this program.

Nobody should charge you to fill out this form

Some companies rank in search results for “patient assistance” and charge a monthly fee to submit paperwork that is free to submit yourself.

You can apply directly. It costs nothing. If a site wants a service fee to enroll you in a manufacturer’s free-drug program, close the tab.

What to say at the pharmacy so the price doesn’t change on you

Prices vary by pharmacy, location, discount network, and quantity, and a coupon must be processed using its specific billing information. The most reliable way to avoid a surprise is to confirm the final out-of-pocket price with the pharmacist before the prescription is dispensed rather than after.

Once a prescription is filled, unwinding it is a hassle. Ask first. Here’s how.

The script

Read it, or read it off your phone. It works.

Five questions worth asking on the phone

Two rules that save headaches

Don’t ask them to run the coupon and your insurance together. It’s one or the other.

Don’t authorize the fill until you’ve heard the final number. You’re allowed to say “let me think about it.” Pharmacists hear it ten times a day.

Is there a generic version of Duavee?

No FDA-approved generic version of Duavee was identified as of July 28, 2026. Duavee is the only product on the US market combining conjugated estrogens with bazedoxifene. The currently listed Duavee patent expires March 10, 2027, which is a patent date rather than an FDA approval date or a guaranteed launch date.

Duavee was approved October 3, 2013 under NDA 022247, developed by Wyeth — a Pfizer subsidiary — with Ligand Pharmaceuticals.

Should you wait for the generic?

No, and that’s not a hedge.

A patent expiration is not a launch date. It’s the earliest point a door could open. Patent challenges, litigation, and licensing deals move these timelines routinely.

And approval isn’t availability. A generic passes through three separate stages that people constantly conflate:

1. FDA approves it — this gets announced
2. It’s manufactured, priced, and distributed — this can take months, or stall
3. Your pharmacy can actually order it — the only stage that affects you

A drug can sit at stage one a long time. “Wait for the generic” is not a plan for hot flashes you’re having this week. And if your pharmacy successfully processes the $30.30 offer, the generic question is a lot less urgent than the fill in front of you.

A cheaper drug is not a generic

This trips people up, so let’s be exact.

An FDA-approved generic has the same active ingredients, strength, dosage form, and route as the brand, and must meet FDA quality and bioequivalence standards. Whether your pharmacist can swap one in automatically also depends on the product’s therapeutic-equivalence rating, your state’s law, and your prescriber’s instructions.

None of that exists for Duavee.

Any cheaper option your prescriber suggests is a different medication — possibly a good one, possibly better for you, but a treatment change, not a brand swap.

Is Duavee discontinued? And why is it hard to find?

As of July 28, 2026, Pfizer’s prescribing information for Duavee remains published, TrumpRx carries a current Pfizer-supported Duavee offer, and Pfizer’s professional site is active. We did not independently complete an FDA Orange Book discontinued-section search, so this page does not claim that no discontinuation record exists. A pharmacy not having Duavee in stock is a different problem from a manufacturer discontinuing it.

One of the sites selling you Duavee coupons says the drug is discontinued

SaveHealth’s Duavee page states the drug was discontinued for business reasons — on the same page where it lists a price and offers you a coupon.

Both can’t be true.

Here’s what we could actually confirm on July 28, 2026: Pfizer’s current prescribing information is published, Duavee carries an active Pfizer-supported offer on a federal website, and Pfizer’s professional site is live.

That’s enough to act on. If a coupon site tells you a drug is gone while selling you a coupon for it, that’s a reason to check elsewhere — not a reason to give up.

What actually happened, because the history explains the strange rules

Duavee really did come off the market for a stretch, and that’s probably where the confusion started.

In May 2020, Pfizer recalled Duavee globally to update its packaging. The issue was shelf-life stability, not the drug’s safety or how well it worked. On June 5, 2023, Pfizer announced Duavee was back in stock in the United States with improved packaging.

The packaging rules

From Duavee’s FDA-approved label:

• Keep it in the original package
• Don’t take a tablet out of the blister until you’re about to swallow it
• Don’t put Duavee in a pill box or pill organizer — this one surprises everyone
• Open one foil pouch at a time
• Write the date you open the pouch on the label
• Don’t use a pouch that’s been open more than 60 days

The label starts each blister package’s 60-day clock when that package is opened, and unopened pouches stay sealed. So a larger quantity isn’t automatically ruled out by that rule.

But that’s a storage fact, not a pricing fact. Ask your pharmacy for a separate 90-tablet quote and confirm whether your discount applies to that quantity — the TrumpRx offer we saw was displayed for 30 tablets. Don’t assume the price scales.

Either way: don’t decant Duavee into a weekly organizer on Sunday the way you might with other pills.

If your pharmacy says they can’t get it

“Very frustrated with two different backorders this summer.”

— Duavee user of eight years, Drugs.com review page (retrieved July 28, 2026)

That’s one person’s experience, from an undated review, and it isn’t evidence of a current nationwide supply problem. But it’s a reminder of something practical: “we don’t have it” doesn’t mean “it doesn’t exist.” Ask whether they can order it, and how long that takes, before you transfer the prescription somewhere else.

What are the cheapest FDA-approved alternatives to Duavee?

Several FDA-approved hormone therapies cost less than Duavee’s published cash price. However, every lower-cost systemic estrogen regimen in the comparison below requires an endometrial protection strategy for a woman with a uterus — usually a progestogen — and none combines Duavee’s progestin-free design with an FDA indication for preventing postmenopausal osteoporosis. Switching is a change of treatment, not a change of brand.

If money is your only concern, Duavee is not the smart buy

We’ll say it straight, because you deserve a real answer instead of a sales pitch.

At published cash prices, Duavee sits near the top of its category. Separate generic estradiol and micronized progesterone may be the lowest-cost systemic route, depending on the formulation, dose, pharmacy, and discount. If you’re on Duavee simply because it’s what your doctor happened to write, and progestogens have never bothered you, ask about the cheaper route. We would genuinely rather you spend less.

That’s the flaw. Now here’s why it may not be your flaw.

Duavee doesn’t use a progestin — and that’s the entire point

Most hormone therapy for a woman with a uterus works like this: estrogen treats the symptoms, and a progestogen (progesterone or a synthetic version called a progestin) is added because estrogen alone can thicken the uterine lining. You take both. That’s the standard arrangement.

Duavee doesn’t make that arrangement.

Instead of a progestin, it pairs conjugated estrogens with bazedoxifene — an estrogen agonist/antagonist, sometimes called a SERM, meaning it behaves like estrogen in some tissues and blocks it in others. Per Duavee’s label, the bazedoxifene component reduces the risk of endometrial hyperplasia that can occur with the conjugated estrogens component. The label also states directly that women taking Duavee should not take progestins, additional estrogens, or additional estrogen agonist/antagonists.

It’s the only FDA-approved product in the US built this way.

On bleeding, Duavee’s own trials reported the share of women with no bleeding at one year at 83% versus 85% on placebo in one study, and 88% versus 84% in another.

And if bone health is part of why you’re on it: Duavee carries an FDA indication for preventing postmenopausal osteoporosis. Not every alternative does.

The alternatives, with the price basis spelled out

We’re showing the exact strength, quantity, and price type for each, because comparing a 28-tablet coupon price to a 30-tablet average price is how people talk themselves into switches that don’t save money.

Note the quantity differences — several of these are 28-tablet packages against Duavee’s 30. Compare 30-day-equivalent totals, not package prices.

Worth pausing on Prempro. Some pages describe it as the cheap alternative. SingleCare’s average cash figure for Prempro ($363.04) is higher than its average cash figure for Duavee ($267.44) — though the comparison flips depending on which price type you use for each. Get both quoted at your own pharmacy before assuming a switch saves anything.

One reason women decline this drug that has nothing to do with money

Duavee’s label states that conjugated estrogens are purified from the urine of pregnant mares. Some women won’t take it for that reason, and it comes up in patient reviews unprompted.

If that’s you, it’s a legitimate reason to prefer something else, and you don’t owe anyone an explanation. Ask your prescriber which alternatives use a different estrogen source.

Please don’t switch on your own

Duavee’s label is direct: no progestins, no additional estrogens, no additional estrogen agonist/antagonists alongside it. Stopping, starting, or stacking hormone therapy without a prescriber is how people get into trouble.

If cost is pushing you toward a change, that’s a conversation — not a decision you make alone at the kitchen table.

Take these three questions to your prescriber:

1. What exactly are we treating with Duavee — symptoms, bone protection, or both?
2. Is there an FDA-approved alternative that does the same job for me, and would it require adding a progestogen?
3. Will you complete the prescriber section of the Pfizer patient assistance application?

That third question is the one most women don’t think to ask, and it’s the one that can take your cost to zero.

If you don’t currently have a prescriber — or yours won’t engage on menopause care — you’ll need one before any of this works. A licensed clinician can evaluate you, prescribe if it’s appropriate, and sign that assistance form.

We’re not recommending Winona or Inner Balance here. Both work primarily with compounded medications, and this is a question about a specific FDA-approved brand-name product. We keep those categories separate.

What does Duavee do, and why can it cost more than alternatives?

Duavee combines conjugated estrogens 0.45 mg with bazedoxifene 20 mg in one daily tablet. It is FDA-approved for women with a uterus to treat moderate-to-severe vasomotor symptoms associated with menopause and to prevent postmenopausal osteoporosis. It is currently brand-only, with no FDA-approved generic identified, and published prices vary substantially by pharmacy and payment route.

If you’re spending money on this, you should know what the money buys. Everything below comes from Duavee’s FDA-approved label.

What the reviews say — including the parts that don’t flatter it

On Drugs.com, Duavee’s overall rating is 6.4 out of 10 across 35 reviews (46% positive, 23% negative). Filtered to hot flashes: 7.5 out of 10 across 15 reviews. Filtered to postmenopausal symptoms: 5.9 out of 10 across 14 reviews, with 43% negative. On WebMD, the overall rating is 3.7. All retrieved July 28, 2026. Note that these are different scales and different denominators — they aren’t directly comparable to each other.

We’re publishing that on the page helping you buy the drug. Small review samples can’t establish how well a medication works, how safe it is, or what your result will be. But you asked what you’re paying for, and honesty is part of the answer.

Who Duavee is not for

Duavee’s label lists these contraindications:

• Undiagnosed abnormal uterine bleeding
• Known, suspected, or past breast cancer
• Known or suspected estrogen-dependent cancer
• Active or past venous thromboembolism (blood clots in the veins)
• Active or past arterial thromboembolic disease, such as stroke or heart attack
• Hypersensitivity to estrogens, bazedoxifene, or any ingredient
• Known hepatic impairment or disease
• Known protein C, protein S, or antithrombin deficiency, or other thrombophilic disorders
• Pregnancy

It is not recommended in women with renal impairment, or in women older than 75 — in both cases because it has not been studied in those populations.

Side effects reported in the trials

Reported in at least 5% of women taking Duavee and more often than placebo: muscle spasms (9% vs 6%), nausea (8% vs 5%), diarrhea (8% vs 5%), indigestion (7% vs 6%), upper abdominal pain (7% vs 5%), throat pain (7% vs 6%), dizziness (5% vs 3%), neck pain (5% vs 4%).

In the label’s pooled studies, discontinuation due to adverse reactions was 7.5% with Duavee and 10.0% with placebo.

A detail about body size

In a single-dose study of 12 women with a BMI of 30 or higher and 12 below 30, bazedoxifene exposure was 13% lower in the higher-BMI group. Because bazedoxifene is the component reducing hyperplasia risk, the label notes that a greater reduction in bazedoxifene than in estrogen may be associated with decreased protection from endometrial hyperplasia, and directs that postmenopausal or unexplained bleeding be evaluated.

That’s twelve women per group. It isn’t a reason to avoid Duavee, and the label gives no different dose based on BMI. What it supports is one simple habit: if you bleed on Duavee, report it promptly, and mention this to your prescriber.

About the label itself

In February 2026, the FDA approved labeling changes for an initial group of menopausal hormone therapy products. We pulled Duavee’s prescribing information on July 28, 2026. It is stamped “Revised: 3/2024” and still contains its boxed warning.

What that means practically: use Duavee’s current label. Changes approved for other products don’t alter what Duavee’s own warning says today. If risk is part of why you’re hesitating, that’s a conversation for your prescriber, using the label in your box.

Does Medicare cover Duavee?

Duavee’s coverage and tier vary by 2026 Part D plan, so the plan’s own formulary is the only reliable answer. Medicare beneficiaries are not eligible for Pfizer’s commercial savings card. Discount cards and manufacturer self-pay offers can be used outside a Part D benefit, but purchases made outside the plan do not count toward the Part D deductible or the $2,100 annual out-of-pocket maximum.

The trap

Say your plan covers Duavee at a $90 copay, and you find a cash price of $45. Feels like an easy win.

Maybe. In 2026, Medicare Part D has a $2,100 annual out-of-pocket maximum for covered drugs. Once you reach it, catastrophic coverage begins and you pay nothing more out of pocket for covered Part D drugs that calendar year.

Every dollar you spend through your plan counts toward that $2,100. Every dollar you spend outside it counts for nothing.

So if you take several medications and you’re likely to reach $2,100 partway through the year, saving $45 a month here can push that ceiling further away and cost you more overall. If you’re nowhere near it, the cheaper fill is probably just cheaper.

Run the math for your whole year, not one fill. Your plan’s member services line can tell you where you stand. Your specific drugs and plan terms decide the answer — not this example.

What Medicare beneficiaries can use

• Your plan’s formulary — check Duavee’s tier and any prior authorization requirements first
• Pfizer’s Patient Assistance Program — government-insured patients may qualify, with the extra 2026 steps described above
• Medicare Extra Help (the Low-Income Subsidy) — this works inside your Part D benefit rather than around it. In 2026, eligible beneficiaries pay up to $5.10 for a generic and $12.65 for a brand-name prescription at participating pharmacies
• A formulary exception, if your plan doesn’t cover Duavee. Your prescriber can request one, with a formal appeals process if the first answer is no

Should you buy Duavee from a pharmacy outside the US?

The FDA’s position is that personal importation of an unapproved drug is illegal in most circumstances, with limited enforcement discretion in narrow cases, and that it cannot assure the safety or effectiveness of medications purchased from unregulated foreign sellers.

Before you consider a foreign seller, there’s a current $30.30 US self-pay offer to check first. Whatever an overseas site is advertising, run that comparison before you take on a risk nobody can verify for you.

If you do buy online, use a US-licensed pharmacy and check these five things: a prescription is required, the pharmacy is licensed in your state, a physical US address is listed, a pharmacist is reachable, and nothing on the site describes a product as “generic Duavee” — because no such approved product exists.

How do you get the lowest Duavee price without insurance?

The sequence is: confirm the prescription details, decide whether the fill goes through insurance or as self-pay, check the current manufacturer-supported offer, compare one recurring coupon price, screen for patient assistance, and confirm the final price with the pharmacy before dispensing. Prices and program terms change, so the check should be repeated at each refill.

If you read nothing else, read this.

1. Confirm what you’re pricing. Duavee 0.45 mg / 20 mg, quantity 30.
2. If you have insurance, check your copay first. Often cheapest. Skip to step 4 if you don’t.
3. Check the current price on trumprx.gov. Save or print the coupon.
4. Screen yourself against the income table above. Household of two under $64,920? Apply.
5. Call your pharmacy with the script. Ask about stock, coupon acceptance, and your final price.
6. Ask for a separate 90-tablet quote and whether your discount covers that quantity.
7. Start the assistance application if you’re in range, and get your prescriber’s signature on their section.
8. Don’t authorize the fill until you’ve heard the final number out loud.
9. Recheck before every refill. These prices move.
10. If it’s still out of reach, take the three questions above to a prescriber and talk through FDA-approved alternatives. See our full provider comparison.

Duavee cost FAQ

How we researched this page

We built this using The HRT Index Verification Standard — our documented process: read every published price, separate FDA-approved from compounded, verify state availability and insurance, and re-check on a fixed schedule.

For this page specifically, that meant normalizing every price to the same product, strength, and quantity; reading Duavee’s FDA-approved label directly instead of a summary of it; reading Pfizer’s actual program terms instead of a coupon site’s description of them; distinguishing average cash prices from recurring coupon prices, first-fill promotions, and manufacturer-supported self-pay offers; and putting a date on every figure.

Where something has to be confirmed at the pharmacy or with a program, we said so instead of guessing. Where we didn’t verify something, we listed it.

When we check again: prices monthly and before any price appears in a headline; Pfizer program terms monthly; income limits every January; label and generic status quarterly and immediately after any FDA or Pfizer announcement.

Think we got something wrong? Tell us at /corrections/. We publish corrections rather than quietly editing.

Sources:trumprx.gov · Duavee FDA prescribing information · pfizerrxpathways.com · Pfizer savings card terms · Pfizer press release, June 5, 2023 · SingleCare · Drugs.com · GoodRx · SaveHealth · Rx.com · medicare.gov · fda.gov · Drugs.com and WebMD patient review pages

One last thing

If you came here because a number at a pharmacy counter made your chest tighten — that reaction was fair. Menopause care in this country costs more than it should, and the discounts get advertised in a way that mostly helps people who already have coverage.

But you’re not out of options. There’s a $30.30 price to check and a free-medication application to start, and you can do both today.

The HRT Index is the independent decision resource for online menopause and HRT care. This page is educational research and is not medical advice. It has not been reviewed by a clinician — see our medical review policy. We may earn a commission from some provider links on this page; see our affiliate disclosure. We earn nothing from the TrumpRx, Pfizer assistance, or discount card links. FDA-approved and compounded medications are always identified separately on this site, and compounded products are never presented as equivalent to FDA-approved ones.